Rett syndrome
MONDO:0010726A severe neurodevelopmental disorder affecting the central nervous system.
Also known as: RTS, RTT, Rett syndrome, Rett syndrome, X-linked dominant, Rett syndrome, atypical, X-linked dominant, Rett syndrome, preserved speech variant, X-linked dominant, Rett’s disease, Rett syndrome, Zappella variant
31 clinical trials for this condition and its sub-types.
Follow this condition to get notified about new trialsBroader categories
-
Could a ketamine drug ease rett syndrome?
Symptom relief CompletedThis early study tested esketamine, a form of ketamine, in 3 girls with Rett syndrome. The goal was to see if weekly infusions over five weeks could improve symptoms and be safe. The trial is complete, but with only 3 participants, it's too small to draw firm conclusions.
Early phase 1 • Sponsor: Children's Hospital of Fudan University • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
-
New parent support programme shows promise for families of children with complex needs
Symptom relief CompletedThis pilot study tested a community-based group programme called 'Encompass' for parents of children under 5 with complex neurodisability. Fifteen parents in East London attended ten group sessions over six months. The study aimed to see if the programme was feasible and acceptab…
Sponsor: City, University of London • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
-
Rett syndrome bone mystery: study probes early osteoporosis
Knowledge-focused CompletedThis study looked at why girls with Rett syndrome often develop weak bones (osteoporosis) at a very young age. Researchers checked bone density, looked at medical history, and measured certain proteins in the blood. The goal was to find risk factors and understand the biological …
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
-
Assessing the safety and efficacy of Full-Spectrum medicinal cannabis plant extract 0.08% THC (NTI164) in the treatment of rett syndrome (RTT)
CompletedThis 18-week open-label study examines the effectiveness of Full-Spectrum Medicinal Cannabis Plant Extract containing 0.08% THC (NTI164) in treating Rett syndrome (RTT) in children and young people. The study aims to determine the impact of NTI164 on RTT symptoms over a 16-week t…
Phase 1/2 • Sponsor: Fenix Innovation Group
Last updated Sep 09, 2026 17:00 UTC