Retinal perforation

This study tests whether injecting a person's own bone marrow stem cells into or near the eye can help treat various retinal and optic nerve diseases, including age-related macular degeneration, retinitis pigmentosa, and glaucoma. Participants receive stem cell injections via dif…

This pilot study compares two surgical techniques for closing idiopathic macular holes: using a Tenon capsule graft versus the standard internal limiting membrane (ILM) flap. Twenty participants will undergo vitrectomy and be assigned to one of the two groups. The study will meas…

This study is testing ten different surgical methods to repair full-thickness macular holes, a condition that blurs central vision. 120 adults will be randomly assigned to one technique during vitrectomy surgery. The main goal is to see which method closes the hole most often and…

This study tests a new gel made from donated amniotic membrane to treat large macular holes, a condition that blurs central vision. The gel is injected into the eye during surgery to help close the hole. Researchers will compare this method to the standard flap technique in 26 ad…

This study tests a new surgical technique for people with macular holes that didn't close after standard treatment. Surgeons take a small piece of the patient's own eye tissue (Tenon's capsule) and use it as a patch to plug the hole. Twenty participants will be followed for 3 mon…

This study tests a new eye imaging device (VG200D OCT) that takes detailed pictures of the retina. It compares these images to standard dye-based images (FA/ICGA) to see if the new device works just as well. About 30 adults with retina problems will take part. The goal is to see …

This study tests a special camera that takes detailed images of the retina using many wavelengths of light. Researchers hope it can find early signs of eye diseases like age-related macular degeneration, diabetic retinopathy, and glaucoma. About 1,000 adults in Melbourne, Austral…

This study tests a laser treatment called OSC/SS to prevent retinal detachment in people with Stickler Syndrome, a genetic condition that raises the risk of vision loss. About 500 children and adults will receive the procedure in one or both eyes and be followed for 5 years. Rese…

This study compares two surgeries for macular holes, a common cause of vision loss. The standard method uses a gas bubble to help the hole close, but the new technique skips the bubble. Researchers want to see if the new method works just as well and makes recovery easier for pat…

This study compares two surgical systems used for combined cataract and vitrectomy eye surgeries. The UNITY VCS system is being tested against the CONSTELLATION system to see which one surgeons find more efficient in real-world operating rooms. About 180 adults needing combined e…

This study is creating a large collection of health information and biological samples (like blood, saliva, and eye tissue) from people with and without retinal diseases. Researchers aim to use this database to better understand conditions like age-related macular degeneration an…

This study uses a special camera (adaptive optics) to take detailed pictures of the back of the eye in people with inherited retinal diseases. Researchers want to see how individual cells change over time and after treatments. About 200 participants aged 5 to 70 will be observed,…

This study gathers eye scan images from 180 people with healthy eyes or eye diseases like glaucoma and retinal disease. The goal is to collect data using a new optical coherence tomography (OCT) device called A10900. No treatment or medication is given. The information will help …

This study tests a special microscope that takes live 3D images inside the eye during surgery. It aims to help surgeons see better when treating conditions like retinal detachment, macular holes, and cataracts. About 262 people will take part, including healthy volunteers and sur…