Amniotic gel could patch macular holes without complex surgery
NCT ID NCT06433284
First seen Apr 05, 2026 · Last updated Jun 19, 2026 · Updated 14 times
Summary
This study tests a new gel made from donated amniotic membrane to treat large macular holes, a condition that blurs central vision. The gel is injected into the eye during surgery to help close the hole. Researchers will compare this method to the standard flap technique in 26 adults. The goal is to see if the gel works as well or better, with fewer complications.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Jakkrit Juhong
RECRUITINGNakhon Si Thammarat, Thasala, 80160, Thailand
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
decellularized human amniotic membrane hydrogel
What this could lead to
If it works, this could offer a safer, easier way to close large macular holes and improve vision without the need for complex flap surgery.
What could go wrong
This is a small, early-stage trial with only 26 participants. The hydrogel is new for eye surgery, so its safety and effectiveness are not yet proven. There may be risks like infection or inflammation.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.