Amniotic gel could patch macular holes without complex surgery

NCT ID NCT06433284

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a new gel made from donated amniotic membrane to treat large macular holes, a condition that blurs central vision. The gel is injected into the eye during surgery to help close the hole. Researchers will compare this method to the standard flap technique in 26 adults. The goal is to see if the gel works as well or better, with fewer complications.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
decellularized human amniotic membrane hydrogel
What this could lead to
If it works, this could offer a safer, easier way to close large macular holes and improve vision without the need for complex flap surgery.
What could go wrong
This is a small, early-stage trial with only 26 participants. The hydrogel is new for eye surgery, so its safety and effectiveness are not yet proven. There may be risks like infection or inflammation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MACULAR HOLES are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Jakkrit Juhong

    RECRUITING

    Nakhon Si Thammarat, Thasala, 80160, Thailand

More trials for these conditions

Other studies related to the condition(s) this trial covers.