Which surgery best fixes macular holes? new trial aims to find out
NCT ID NCT07606404
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing ten different surgical methods to repair full-thickness macular holes, a condition that blurs central vision. 120 adults will be randomly assigned to one technique during vitrectomy surgery. The main goal is to see which method closes the hole most often and gives the best eyesight, measured at one week, one month, and one year after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Pars plana vitrectomy surgery with various techniques, plus optional use of platelet-rich plasma or amniotic membrane graft
What this could lead to
If successful, this study could identify the most effective surgical technique for closing macular holes and improving vision, guiding future standard care.
What could go wrong
This is a single-center trial with 120 participants, so results may not apply to all patients. Different techniques may work better for different hole sizes, and individual outcomes vary.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Kazakh Eye Research Institute
RECRUITINGAlmaty, Almaty, 050042, Kazakhstan
Contact Phone: •••-•••-•••• Email: •••••@•••••