Which surgery best fixes macular holes? new trial aims to find out
NCT ID NCT07606404
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing ten different surgical methods to repair full-thickness macular holes, a condition that blurs central vision. 120 adults will be randomly assigned to one technique during vitrectomy surgery. The main goal is to see which method closes the hole most often and gives the best eyesight, measured at one week, one month, and one year after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Pars plana vitrectomy surgery with various techniques, plus optional use of platelet-rich plasma or amniotic membrane graft
- What this could lead to
- If successful, this study could identify the most effective surgical technique for closing macular holes and improving vision, guiding future standard care.
- What could go wrong
- This is a single-center trial with 120 participants, so results may not apply to all patients. Different techniques may work better for different hole sizes, and individual outcomes vary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Kazakh Eye Research Institute
RECRUITINGAlmaty, Almaty, 050042, Kazakhstan
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