REM sleep behavior disorder
MONDO:0005937A disorder characterized by episodes of vigorous and often violent motor activity during rem sleep (sleep, rem). The affected individual may inflict self injury or harm others, and is difficult to awaken from this condition. Episodes are usually followed by a vivid recollection of a dream that is consistent with the aggressive behavior. This condition primarily affects adult males. (From Adams et al., Principles of Neurology, 6th ed, p393)
68 clinical trials for this condition and its sub-types.
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Broader categories
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Lifestyle overhaul may slow Parkinson's onset
Prevention Not yet recruitingThis study tests whether a 6-month program combining exercise, Mediterranean diet, sleep counseling, and cognitive training can help people with early Parkinson's or a sleep disorder (RBD) stick to healthy habits. Researchers will track how well 99 participants follow the program…
Phase: NA • Sponsor: University Hospital Schleswig-Holstein • Aim: Prevention
Last updated Jun 27, 2026 08:06 UTC
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A sip for better sleep? beverage put to the test
Symptom relief Not yet recruitingThis trial tests whether a concentrated beverage taken daily for 28 days can improve sleep quality in adults aged 18 to 60 with mild sleep issues. Participants keep sleep diaries and complete questionnaires on sleep quality and fatigue. The study uses a single-arm design, meaning…
Phase: NA • Sponsor: Sirio Pharma Co., Ltd • Aim: Symptom relief
Last updated Jul 26, 2026 00:00 UTC
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Can a narcolepsy drug fix ICU sleep problems?
Symptom relief Not yet recruitingThis study tests whether a drug called gamma-hydroxybutyrate (GHB) can help intensive care patients get better deep sleep. Sleep problems are very common in the ICU and can lead to serious issues like confusion and longer recovery. The trial will give GHB or a placebo to 24 adult…
Phase: PHASE2 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
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Can a bedtime pill fix sleep troubles in kids with anorexia?
Symptom relief Not yet recruitingThis study tests a slow-release melatonin (PedPRM) in 120 children aged 6 to 18 who have anorexia nervosa and trouble sleeping. Participants take either melatonin or a placebo for 13 weeks. The goal is to see if it safely improves total sleep time and related symptoms like anxiet…
Phase: PHASE3 • Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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Smartwatch vibration therapy tested for warfighter nightmares and insomnia
Symptom relief Not yet recruitingThis study tests whether a special smartwatch can improve sleep in warfighters who have trouble sleeping due to PTSD, traumatic brain injury, or stress. The watch detects signs of stress during sleep, like a fast heart rate, and gives gentle vibrations to calm the body without wa…
Phase: NA • Sponsor: Uniformed Services University of the Health Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 12:25 UTC
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Smartwatch AI could spot Parkinson's years before symptoms
Knowledge-focused Not yet recruitingThis study tests whether an artificial intelligence model can estimate a person's risk of developing Parkinson's disease. Participants aged 50 and older who have certain early warning signs—like REM sleep behavior disorder, drops in blood pressure upon standing, or reduced sense …
Sponsor: Queen Mary University of London • Aim: Knowledge-focused
Last updated Jul 22, 2026 00:00 UTC
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New study aims to unravel Parkinson's protein mysteries
Knowledge-focused Not yet recruitingThis study looks at how abnormal proteins, like alpha-synuclein and tau, build up and affect brain function in people with Parkinson's disease. Researchers will use brain scans, blood tests, and skin biopsies to track these changes. The goal is to find better ways to diagnose and…
Phase: NA • Sponsor: University of Pavia • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC