Refractive error
MONDO:0004892A defect in the focusing of light on the retina as in astigmatism, myopia, or hyperopia.
400 clinical trials for this condition and its sub-types, 82 tagged with Refractive error itself.
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Sub-types of Refractive error
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Myopia 259 trials · 274 incl. sub-types
30 sub-types
- Degenerative myopia 38 trials
- Myopia, high, with cataract and vitreoretinal degeneration 1 trial
- Myopia 1, X-linked 0 trials
- Myopia 10 0 trials
- Myopia 11, autosomal dominant 0 trials
- Myopia 12, autosomal dominant 0 trials
- Myopia 13, X-linked 0 trials
- Myopia 14 0 trials
- Myopia 15, autosomal dominant 0 trials
- Myopia 16, autosomal dominant 0 trials
- Myopia 17, autosomal dominant 0 trials
- Myopia 18, autosomal recessive 0 trials
- Myopia 19, autosomal dominant 0 trials
- Myopia 2, autosomal dominant 0 trials
- Myopia 20, autosomal dominant 0 trials
- Myopia 21, autosomal dominant 0 trials
- Myopia 22, autosomal dominant 0 trials
- Myopia 23, autosomal recessive 0 trials
- Myopia 24, autosomal dominant 0 trials
- Myopia 25, autosomal dominant 0 trials
- Myopia 26, X-linked, female-limited 0 trials
- Myopia 27 0 trials
- Myopia 28, autosomal recessive 0 trials
- Myopia 3, autosomal dominant 0 trials
- Myopia 5, autosomal dominant 0 trials
- Myopia 6 0 trials
- Myopia 7 0 trials
- Myopia 8 0 trials
- Myopia 9 0 trials
- Schizophrenia 16 0 trials
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Astigmatism 78 trials · 81 incl. sub-types
2 sub-types
- Irregular astigmatism 5 trials
- Regular astigmatism 2 trials
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Presbyopia 63 trials
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Hyperopia 27 trials
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Anisometropia 7 trials
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Aniseikonia 0 trials
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Transient refractive change 0 trials
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Eye surgery showdown: device vs manual marking for sharper vision
Disease control Not yet recruitingThis trial tests whether a device called OcuLign, which automatically adjusts for eye rotation during SMILE surgery, corrects astigmatism better than the standard manual marking method. Adults aged 18 to 40 with stable myopia and astigmatism will have one eye treated with each me…
Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
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New spectacle lenses aim to make myopia control more comfortable for kids
Disease control Not yet recruitingThis study compares two types of spectacle lenses designed to slow the progression of myopia (nearsightedness) in children aged 6 to 10. The goal is to see if the new test lenses are as comfortable and easy to adapt to as the control lenses during the first two weeks of wear. Chi…
Sponsor: Essilor International • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC
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New glasses aim to slow nearsightedness in children
Disease control Not yet recruitingThis study tests two new types of multifocal glasses designed to manage myopia (nearsightedness) in children aged 8 to 15. Twenty kids who already wear myopia-control glasses will try each new design for a short time to see how well they see and how comfortable they feel. The goa…
Sponsor: Myoptechs, Inc • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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Can a smart device predict how a Child's eye grows?
Diagnosis Not yet recruitingResearchers are testing a new device called SmartEyes that measures refractive errors, which are vision problems like nearsightedness. The study involves 200 children and teens aged 6 to 17 who need eye exams. The trial compares SmartEyes with standard equipment and subjective re…
Sponsor: The Hong Kong Polytechnic University • Aim: Diagnosis
Last updated Sep 05, 2026 00:00 UTC
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New digital eye test in turkish put to the test
Diagnosis Not yet recruitingThis study checks if a Turkish version of the DDIVAT digital vision test gives the same results as the standard Snellen eye chart. About 200 Turkish-speaking adults, with or without glasses, will take both tests. No drugs or procedures are involved, and there are no risks.
Sponsor: Trakya University • Aim: Diagnosis
Last updated Jun 27, 2026 08:01 UTC
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Texts and calls could save sight: pakistan study tests referral boost
Prevention Not yet recruitingThis study tests whether a structured referral tracking program helps adults in Pakistan complete follow-up eye care after community screenings. 500 participants will receive either standard referral or extra support like counseling and weekly reminders. The goal is to prevent bl…
Sponsor: Health Services Academy, Islamabad, Pakistan • Aim: Prevention
Last updated Jun 27, 2026 13:03 UTC
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Could a medicated contact lens ease pain after laser eye surgery?
Symptom relief Not yet recruitingThis trial compares pain relief from bandage contact lenses soaked in the anti-inflammatory drug ketorolac versus plain lenses after photorefractive keratectomy (PRK), a type of laser eye surgery. PRK often causes significant pain in the first few days as the cornea heals. The st…
Sponsor: Madina Teaching Hospital Faisalabad • Aim: Symptom relief
Last updated Jul 17, 2026 00:00 UTC
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Tailored eye incisions may cut glasses dependence after cataract surgery
Symptom relief Not yet recruitingThis study tests whether placing surgical cuts in specific parts of the cornea during cataract surgery can reduce astigmatism (blurry vision from an irregularly shaped cornea) and lower the need for glasses afterward. About 100 people with cataracts and astigmatism will be random…
Sponsor: Linkoeping University • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Three eye scanners race to settle whether laser capsulotomy shifts the lens
Knowledge-focused Not yet recruitingAfter cataract surgery, the membrane holding the artificial lens can turn cloudy, blurring vision. The standard fix is a quick laser procedure called Nd:YAG capsulotomy, but doctors disagree on whether it shifts the lens. This study measures the lens position in 80 people using t…
Sponsor: Vienna Hospital Association • Aim: Knowledge-focused
Last updated Sep 05, 2026 00:00 UTC
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Eye math put to the test: can any formula predict the perfect lens for extreme eyes?
Knowledge-focused Not yet recruitingThis study checks how accurately eight different formulas predict the lens power needed for people with very short or very long eyes after cataract surgery. Researchers will measure the actual vision result and compare it to what each formula predicted. The goal is to find which …
Sponsor: Vienna Hospital Association • Aim: Knowledge-focused
Last updated Jul 26, 2026 00:00 UTC
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Could early vision screening in preschoolers prevent lifelong blindness?
Knowledge-focused Not yet recruitingThis study follows 1,000 preschool children (ages 0-6) with refractive errors like nearsightedness, farsightedness, or astigmatism. Researchers aim to map how these conditions progress, identify related health issues, and find the best ways to correct vision early. The goal is to…
Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University • Aim: Knowledge-focused
Last updated Jul 17, 2026 00:00 UTC
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Large survey aims to uncover hidden vision and hearing loss in older adults
Knowledge-focused Not yet recruitingThis study surveys about 2,800 adults aged 65 and older in Xinxing County, China, to measure how many have untreated vision or hearing problems. Participants receive eye exams, hearing tests, and questionnaires. The goal is to provide local health services with data to improve ca…
Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University • Aim: Knowledge-focused
Last updated Jul 12, 2026 00:00 UTC
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Eye study aims to map corneal thickness in common vision problems
Knowledge-focused Not yet recruitingThis study will use a special imaging device (AS-OCT) to measure the thickness of the cornea's outer layer in 360 adults with nearsightedness, farsightedness, astigmatism, or normal vision. The goal is to see if different vision problems have unique thickness patterns. Participan…
Sponsor: Sohag University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New study aims to help more people in rural assam get the eye care they need
Knowledge-focused Not yet recruitingThis study looks at why many people in rural Assam who are referred for eye care don't make it to the hospital for treatment. Researchers will test new ways to help patients complete their referrals, like providing transport and reminders. The goal is to increase the number of pe…
Sponsor: Seva Canada Society • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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New study aims to sharpen contact lens prescriptions for astigmatism
Knowledge-focused Not yet recruitingThis study looks at whether a new, objective way to fit toric contact lenses (for astigmatism) gives the same results as the traditional subjective method. About 45 adults with astigmatism will have their lens prescription checked both ways. The goal is to see if the new method c…
Sponsor: CooperVision International Limited (CVIL) • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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New study aims to sharpen vision after laser eye surgery
Knowledge-focused Not yet recruitingThis study will measure how pupil size and eye shape affect visual quality in 300 people with normal eyes or after refractive surgery. Researchers will use questionnaires and special instruments to track symptoms and eye measurements. The goal is to better understand what influen…
Sponsor: Tianjin Eye Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Premature baby eye treatments under the microscope
Knowledge-focused Not yet recruitingThis study looks at children born prematurely who had retinopathy of prematurity (ROP), a disease that can cause blindness. Some were treated with laser, others with injections, and some had ROP but no treatment. Researchers will compare their vision and retina structure to see w…
Sponsor: Oslo University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Nursing students get a brain boost: new program aims to sharpen critical thinking
Knowledge-focused Not yet recruitingThis study tests a special program designed to improve critical thinking, reflective thinking, and motivation to learn in nursing students. About 243 students will take part in the program, which focuses on building skills like problem-solving and open-mindedness. Researchers wil…
Sponsor: Mansoura University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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3,000 residents to help map eye health in xinxing county
Knowledge-focused Not yet recruitingThis study will check the eyes of 3,000 people in Xinxing County, including schoolchildren, seniors, and people with diabetes. The goal is to measure how common vision problems like nearsightedness and cataracts are, and how well they are being treated. Participants will have sim…
Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Eye shape linked to optic nerve changes in new study
Knowledge-focused Not yet recruitingThis study looks at how the length of the eye and the amount of nearsightedness or farsightedness relate to the health of the optic nerve and surrounding layers. Researchers will use a special camera (OCT) to take detailed images of the eye in 266 adults. The goal is to better un…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC