Pyelonephritis
MONDO:0006939An inflammatory process affecting the kidney. The cause is most often bacterial, but may also be fungal in nature. Signs and symptoms may include fever, chills, flank pain, painful and frequent urination, cloudy or bloody urine, and confusion.
Also known as: kidney infection, pyometrium
25 clinical trials for this condition and its sub-types.
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Broader categories
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New antibiotic vabomere tested in kids with tough UTIs
Disease control OngoingThis study tests the safety of an antibiotic called Vabomere in children aged 3 months to 12 years who have complicated urinary tract infections, including kidney infections. The children receive the medicine through an IV while in the hospital. Researchers monitor for side effec…
Phase: PHASE2 • Sponsor: Rempex (a wholly owned subsidiary of Melinta Therapeutics, LLC) • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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Kidney transplant patients' immune response to common virus tracked after drug switch
Knowledge-focused OngoingThis study follows 28 kidney transplant recipients who are switching from one anti-rejection drug (anticalcineurin) to another (belatacept). Researchers want to see how this change affects the immune system's ability to fight the common CMV virus. Participants will have blood tes…
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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New test combo could slash unnecessary antibiotic use in sepsis
Knowledge-focused OngoingThis study tests whether using rapid, advanced lab tests to identify the exact bacteria causing a severe infection can help doctors choose the right antibiotics faster. About 190 adults with sepsis in Greek ICUs will either get standard care or the new testing strategy. The goal …
Phase: PHASE3 • Sponsor: Hellenic Institute for the Study of Sepsis • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC