Pulmonary valve stenosis
MONDO:0006936The pathologic narrowing of the orifice of the pulmonary valve. This lesion restricts blood outflow from the right ventricle to the pulmonary artery. When the trileaflet valve is fused into an imperforate membrane, the blockage is complete.
44 clinical trials for this condition and its sub-types.
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Broader categories
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New Blood-Clot monitor could cut transfusions in heart surgery
Disease control OngoingThis study tests whether a bedside device called Quantra can help doctors decide when to give blood transfusions during complex heart surgery. The device measures how well a patient's blood clots in real time. Researchers hope this will reduce the number of blood products (like r…
Phase: NA • Sponsor: The Cleveland Clinic • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New heart valve could spare patients from Open-Heart surgery
Disease control OngoingThis study tests a new device called the PULSTA valve, which is placed inside the heart through a tube in a blood vessel, avoiding open-heart surgery. It is for 58 people with a leaky or narrowed pulmonary valve, often due to a birth defect. The goal is to see if the valve is saf…
Phase: NA • Sponsor: Taewoong Medical Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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New heart valve device offers hope for patients with congenital defects
Disease control OngoingThis study is testing a new device called the GORE PV1 to replace the pulmonary valve and rebuild the right ventricular outflow tract in people with congenital heart defects. The device is designed to improve blood flow from the heart to the lungs. The study includes 15 participa…
Phase: NA • Sponsor: W.L.Gore & Associates • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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New heart valve could spare congenital patients from repeat surgeries
Disease control OngoingThis study is testing a new heart valve, called the SAPIEN 3, in 150 people with congenital heart defects whose existing heart valves are not working properly. The valve is placed using a thin tube (catheter) through a blood vessel, avoiding open-heart surgery. The goal is to see…
Sponsor: Edwards Lifesciences • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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Heart surgery recovery study pulled before it began
Knowledge-focused TerminatedThis study was designed to see if early mobilization and a simple bottle-based breathing device (Bottle-P.E.P.) could improve breathing and physical function in people recovering from heart valve surgery. The trial was withdrawn before enrolling any participants, so no results ar…
Phase: NA • Sponsor: Istanbul Saglik Bilimleri University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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New patch could replace needles for monitoring heart patients
Knowledge-focused OngoingThis study tests a new sensor worn on the skin that measures lactate levels without needles. It involves 20 adults recovering from heart bypass or valve surgery. The goal is to see if the sensor works as well as standard blood tests, which could make monitoring more comfortable a…
Phase: NA • Sponsor: Queen Mary University of London • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Heart valve procedure: who might face problems later?
Knowledge-focused OngoingThis study follows 50 people who had a minimally invasive procedure to widen a narrowed heart valve (pulmonary balloon valvuloplasty). The goal is to see how often the right side of the heart struggles afterward and what factors might predict that. Researchers will track changes …
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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New imaging tool could make heart bypass safer during valve surgery
Knowledge-focused OngoingThis study compares two methods for deciding which blocked heart arteries need bypass during valve surgery. The standard method uses angiography (X-ray dye), while the new method uses a computer calculation called QFR. About 792 patients will be randomly assigned to one method, a…
Phase: NA • Sponsor: Ruijin Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:08 UTC