Protein-energy malnutrition

This study tests whether adding choline to a peanut-based therapeutic food improves cognitive development in 1,500 Malawian children aged 6-59 months with severe acute malnutrition. Half get standard food, half get food with extra choline. All also receive amoxicillin. The goal i…

This study tests whether adding choline (a nutrient found in eggs and meat) to a standard food supplement helps children with moderate acute malnutrition avoid becoming severely malnourished. About 1,500 children aged 6 to 59 months in Malawi will receive either the standard supp…

This study tests whether giving severely malnourished children lower-calorie feeds during the first stage of hospital treatment is safe and helps them survive. About 135 children aged 6 months to 5 years will receive either a standard feed or one of two reduced-calorie feeds. Res…

Severe acute malnutrition affects millions of children worldwide and often leads to death after hospital discharge. This phase 3 trial tests whether giving a combination of antibiotics (rifampicin, azithromycin, isoniazid, and vitamin B6) for several weeks can lower the risk of d…

This study looks at how well children aged 1 to 16 tolerate and accept new nutritional feeds made from real food ingredients. The feeds are given through a tube or as a drink. Researchers will track stomach issues like pain, bloating, and nausea over 28 days. The goal is to see i…

This pilot study in Guinea-Bissau will see if monthly growth checks by local health workers can reduce severe malnutrition in children aged 6 months to 5 years. About 400 children from two villages will take part. The study also compares three ways to measure arm size to find the…