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Can a nutrient in eggs keep malnourished kids from getting worse?

NCT ID NCT06214897

Disease control Sponsor: Washington University School of Medicine Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 13, 2026 · Updated 2 times

Summary

This study tests whether adding choline (a nutrient found in eggs and meat) to a standard food supplement helps children with moderate acute malnutrition avoid becoming severely malnourished. About 1,500 children aged 6 to 59 months in Malawi will receive either the standard supplement or one with extra choline for up to 12 weeks. Researchers will compare how many children worsen, recover, or gain weight.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

1,515 people

The number who actually took part.

Started

Mar 2024

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

6 to 59 months

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 6-59 months of age * uncomplicated MAM (mid-upper arm circumference (MUAC) ≥ 11.5 cm and \< 12.5 cm and/or weight-for-length z-score (WLZ) ≥ -3 and \< -2) * availability for the duration of the study with no plan to move from the catchment area of a participating clinic Exclusion Criteria: * presence of nutritional edema * features of complicated MAM, such as mental status changes or breathing issues * participation in another feeding program * known allergy to study food ingredient * intention to move away from catchment area within 9 months * developmental delay * presence of a chronic severe medical condition (other than TB or HIV) such as congenital heart disease

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Conditions

The condition(s) this trial relates to.

nutritional deficiency disease protein-energy malnutrition prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Moderate acute malnutrition

Contacts and locations

Locations

  • Chikonde Health Center

    Chikonde, Malawi

  • Chipolonga Health Center

    Chipolonga, Malawi

  • Makhwira Health Center

    Makhwira, Malawi

  • Mbiza Health Clinic

    Mbiza, Malawi

  • Milonde Health Center

    Milonde, Malawi

  • Mitondo Health Center

    Mitondo, Malawi

  • Muloza Health Clinic

    Muloza, Malawi

  • Namasalima Health Center

    Namasalima, Malawi

  • Naphimba Health Center

    Naphimba, Malawi

  • Nkhate Health Clinic

    Nkhate, Malawi

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