Primitive neuroectodermal tumor
MONDO:0005462A malignant neoplasm that originates in the neuroectoderm. The neuroectoderm constitutes the portion of the ectoderm of the early embryo that gives rise to the central and peripheral nervous systems and includes some glial cell precursors.
Also known as: PNET, neuroectodermal neoplasm, neuroectodermal tumor, neuroectodermal tumour, primitive neuroectodermal neoplasm, primitive neuroectodermal tumor, primitive neuroectodermal tumor (PNET), primitive neuroectodermal tumour (PNET)
1645 clinical trials for this condition and its sub-types, 14 tagged with Primitive neuroectodermal tumor itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Primitive neuroectodermal tumor
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Neuroblastic tumor 3 trials · 206 incl. sub-types
3 sub-types
- Neuroblastoma 198 trials · 204 incl. sub-types Sub-types →
- Ganglioneuroblastoma 20 trials · 21 incl. sub-types Sub-types →
- Ganglioneuroma 5 trials Sub-types →
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Central nervous system primitive neuroectodermal neoplasm 8 trials · 24 incl. sub-types
8 sub-types
- Intracranial primitive neuroectodermal tumor 0 trials · 8 incl. sub-types Sub-types →
- Childhood central nervous system primitive neuroectodermal neoplasm 6 trials Sub-types →
- Ependymoblastoma 5 trials Sub-types →
- Ganglioneuroma 5 trials Sub-types →
- Central nervous system tumor with bcor internal tandem duplication 1 trial
- Adult central nervous system primitive neuroectodermal neoplasm 0 trials Sub-types →
- Spinal cord neuroblastoma 0 trials
- Spinal cord primitive neuroectodermal tumor 0 trials
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Peripheral primitive neuroectodermal tumor 7 trials · 8 incl. sub-types
3 sub-types
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Melanotic neuroectodermal tumor 0 trials
Most studied deeper sub-types
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Can the Body's own immune cells beat a recurrent brain tumor?
Cure CompletedThis phase 2 trial tests whether giving patients their own tumor-specific immune cells, along with a dendritic cell vaccine, can help fight recurrent medulloblastoma or primitive neuroectodermal tumors. Participants receive these treatments after high-dose chemotherapy and a stem…
Phase 2 • Sponsor: University of Florida • Aim: Cure
Last updated Aug 15, 2026 00:00 UTC
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Immune cells injected directly into brain show promise for kids with tough tumors
Disease control CompletedThis early-stage study tested a new treatment for children and young adults with brain tumors that came back or didn't respond to standard therapy. Doctors took the patients' own immune cells, modified them to recognize a protein called EGFR on tumor cells, and injected them dire…
Phase 1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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New study tracks Radiation's toll on Kids' brains
Knowledge-focused CompletedThis study followed 76 children with brain tumors to learn how radiation therapy affects their quality of life, thinking, and body functions over time. Researchers collected blood, urine, and MRI scans before and after treatment, along with tests of memory, behavior, vision, and …
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Sep 19, 2026 00:00 UTC
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Large study digs into rare brain tumors to uncover clues
Knowledge-focused CompletedThis study gathered information from 326 adults with rare central nervous system tumors, such as medulloblastoma and ependymoma. Participants completed surveys about their symptoms, treatments, and lifestyle, and provided a saliva sample for genetic analysis. The goal was to lear…
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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Can a Child's tumor DNA guide better cancer treatment?
Knowledge-focused CompletedThis study tested whether analyzing the DNA and RNA of a child's tumor could help doctors choose personalized treatments. It included 186 children with relapsed or hard-to-treat cancers like neuroblastoma and brain tumors. The goal was to see if this approach was feasible and saf…
Sponsor: Giselle Sholler • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC