Primary syphilis
MONDO:0002896The subclinical or symptomatic stage of syphilis, occurring at an average of three weeks after contact with an infected individual. It manifests with one or more painless, indurated ulcers (chancres) of the skin or mucous membranes at the site of inoculation. These lesions heal spontaneously within a few weeks.
Also known as: early syphilis, symptomatic
60 clinical trials for this condition and its sub-types.
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New syphilis combo treatment tested in HIV patients – trial cut short
Disease control TerminatedThis study looked at two different antibiotic combinations for treating early syphilis in people living with HIV. One group received a single shot of ceftriaxone plus a week of doxycycline pills, while the other got the standard single shot of penicillin plus the same doxycycline…
Phase: PHASE4 • Sponsor: National Taiwan University Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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Sticker shock: simple reminder may cut unnecessary IV antibiotic use
Knowledge-focused TerminatedThis study tested whether placing a reminder sticker on the charts of adult hospital patients receiving IV fluoroquinolone antibiotics would encourage doctors to switch them to oral pills sooner. The trial involved 168 patients at a single hospital in Thailand. Unfortunately, the…
Phase: NA • Sponsor: Mahidol University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC