Primary osteolysis

This study tests whether a plaster containing uracil can reduce symptoms of hand-foot syndrome (HFS) in adults undergoing chemotherapy. HFS causes redness, swelling, and pain on the hands and feet. Researchers will compare the uracil plaster to a standard soothing cream. About 80…

Researchers are taking a blood sample from one child with Hutchinson-Gilford progeria syndrome, a rare condition that causes rapid premature aging. They plan to turn those blood cells into stem cells and then into disease-relevant cells like muscle and nerve cells. This lab model…

This study will look at 35 children with joint problems that are not caused by inflammation, such as stiffness or deformity. Researchers will use exams, lab tests, and imaging to find the true cause, which could be rare genetic conditions like mucopolysaccharidoses or osteogenesi…