Primary angle-closure glaucoma
MONDO:0001868An angle-closure glaucoma characterized by closure of the anterior chamber angle by an intrinsic defect such that aqueous outflow is blocked and the intraocular pressure becomes inappropriately elevated leading to optic nerve damage and visual field loss. Primary angle-closure glaucoma has symptom progressive peripheral vision loss, decreased vision, and pain, redness, and headache in acute cases. Primary angle closure glaucoma can be caused by anatomically narrow angle, defects in the trabecular meshwork, and iris abnormalities. Primary angle-closure glaucoma has a strong genetic component.
24 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
-
New eye implant aims to ease glaucoma pressure
Disease control OngoingThis study tests a small implant placed inside the eye to help drain fluid and lower pressure in people with open-angle or narrow-angle glaucoma. It is for adults whose eye pressure is not well controlled with eye drops. The main goal is to see if the implant safely reduces press…
Phase: NA • Sponsor: Ciliatech • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
-
Tiny implant could ease glaucoma pressure
Disease control OngoingThis study tests a new device called the VividWhite Glaucoma Implant, which is surgically placed in the eye to help lower pressure in people with glaucoma. Sixty-five participants will be followed for 12 months to see if the implant safely reduces eye pressure and lessens the nee…
Phase: NA • Sponsor: VividWhite Pty Ltd • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
-
Tiny steroid implant may boost glaucoma surgery success
Disease control OngoingThis pilot study tests whether placing a slow-release steroid insert (Yutiq) during glaucoma drainage surgery helps reduce scarring and keeps eye pressure lower. About 5 adults with glaucoma will receive the implant along with their surgery. Researchers will compare their pressur…
Phase: EARLY_PHASE1 • Sponsor: Sanjay Asrani • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
-
Laser showdown: where to zap the iris for better glaucoma control?
Disease control OngoingThis study tests two different spots (temporal vs inferior) for a YAG laser iridotomy in people with angle-closure glaucoma. Each patient gets one spot in each eye, and doctors track pressure, symptoms, and complications over six months. The goal is to find which location is safe…
Phase: NA • Sponsor: Isfahan University of Medical Sciences • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
-
Free eye tests aim to catch vision loss early in harlem and washington heights
Knowledge-focused OngoingThis study offers free vision screenings to underserved adults over 40 living in affordable housing in Harlem and Washington Heights. The goal is to find eye problems like glaucoma, cataracts, and diabetic retinopathy early and connect people with follow-up care. About 749 partic…
Phase: NA • Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC