Priapism
MONDO:0004745Persistent and usually painful erection that lasts for at least four hours in the absence of physical or psychological stimulation, which can be caused by hematologic disorders, including sickle cell disease and leukemia, spinal cord injuries, and medications.
Also known as: mentulagra, low-flow priapism
10 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New hope for sickle cell patients: drug cuts painful erections
Disease control CompletedThis study tested a drug called crizanlizumab in 36 men with sickle cell disease who suffer from priapism—painful erections lasting an hour or more. The goal was to see if the drug could reduce how often these events happen. Participants received the drug by IV and reported their…
Phase: PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Could an antioxidant shield the penis from damage after a painful erection?
Knowledge-focused CompletedThis study in 18 rats investigates whether alpha lipoic acid, a natural antioxidant, can protect penile tissue from damage caused by restoring blood flow after a prolonged painful erection (priapism). Researchers will measure various markers of oxidative stress and inflammation i…
Phase: NA • Sponsor: Trabzon Kanuni Education and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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New french questionnaire aims to better assess male sexual health
Knowledge-focused CompletedThis study translated a detailed questionnaire about male sexual function into French and tested it with 14 men who have sexual dysfunction. The goal was to see if the questions were clear and easy to understand. This is a first step toward having a reliable tool for French-speak…
Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC