Could an antioxidant shield the penis from damage after a painful erection?
NCT ID NCT07391709
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study in 18 rats investigates whether alpha lipoic acid, a natural antioxidant, can protect penile tissue from damage caused by restoring blood flow after a prolonged painful erection (priapism). Researchers will measure various markers of oxidative stress and inflammation in blood and tissue. The goal is to see if this simple supplement might one day help prevent long-term harm in men who experience this condition.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
alpha lipoic acid
What this could lead to
If it works, this could point toward a treatment to prevent tissue damage from prolonged painful erections in humans.
What could go wrong
This is a very early animal study with only 18 rats. Results may not apply to humans, and the treatment may not be effective or safe.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Karadeniz Technical University Experimental Animal Research Center
Trabzon, Turkey (Türkiye)