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Post-thrombotic syndrome

MONDO:0005928

A condition characterized by a chronically swollen limb, often a leg with stasis dermatitis and ulcerations. This syndrome can appear soon after phlebitis or years later. Postphlebitic syndrome is the result of damaged or incompetent venous valves in the limbs. Distended, tortuous varicose veins are usually present. Leg pain may occur after long period of standing.

Also known as: postphlebitic syndrome

16 clinical trials for this condition and its sub-types.

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Broader categories

Cardiovascular disorder (1051) Disease (680) Vascular disorder (135) Venous insufficiency (47) Vein disorder (15) Human disease (14) Vascular insufficiency disorder (1) Disease by body system or component (0)
Trials to join now! 9 Not yet recruiting 3 Not yet finished but already full! 1 Completed 3
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  • New hope for chronic leg pain: catheter procedure could reduce Post-Clot disability

    Disease control Ongoing

    This study tests whether a catheter-based procedure can reduce the severity of post-thrombotic syndrome (PTS) — a painful, long-term leg condition that can follow a deep vein clot. About 225 adults with disabling PTS and a blocked iliac vein will receive either the procedure plus…

    Phase: NA • Sponsor: Washington University School of Medicine • Aim: Disease control

    Last updated Jun 27, 2026 09:00 UTC

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