Polyostotic fibrous dysplasia

This study tested a drug called burosumab in 12 people with fibrous dysplasia who also had low blood phosphate, which can make bones weaker. Participants injected the drug at home once or twice a month for 48 weeks. The main goal was to see if the drug could raise phosphate level…

This study tested a drug called denosumab in 15 children aged 4 to 14 with fibrous dysplasia, a rare bone disease that causes weak spots and fractures. The goal was to see if the drug could stop bone lesions from growing during childhood. Participants received injections every 4 …

This study tested a drug called tocilizumab for people with fibrous dysplasia of bone who still had pain after standard treatment. The drug blocks a protein linked to bone breakdown. Nineteen adults participated in this small, early-stage trial to see if the drug could reduce bon…

This study aims to understand why people with fibrous dysplasia of bone or McCune-Albright syndrome experience chronic pain. Researchers will compare pain responses in 40 adults (20 patients and 20 healthy volunteers) using heat and cold tests. The goal is to see if the nervous s…

This study looked at why people with Fibrous Dysplasia/McCune-Albright Syndrome feel pain, even when their bones don't show much damage. Researchers used brain scans and pain questionnaires in 37 patients and healthy volunteers. The goal was to understand the root causes of pain,…