Could a bone drug halt skeletal damage in kids with rare disease?

NCT ID NCT05419050

First seen Jan 23, 2026 · Last updated May 10, 2026 · Updated 15 times

Summary

This study tested a drug called denosumab in 15 children aged 4 to 14 with fibrous dysplasia, a rare bone disease that causes weak spots and fractures. The goal was to see if the drug could stop bone lesions from growing during childhood. Participants received injections every 4 weeks for 48 weeks and were monitored with scans and lab tests.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.