Could a bone drug halt skeletal damage in kids with rare disease?

NCT ID NCT05419050

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a drug called denosumab in 15 children aged 4 to 14 with fibrous dysplasia, a rare bone disease that causes weak spots and fractures. The goal was to see if the drug could stop bone lesions from growing during childhood. Participants received injections every 4 weeks for 48 weeks and were monitored with scans and blood tests.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

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Other studies related to the condition(s) this trial covers.