Could a bone drug halt skeletal damage in kids with rare disease?
NCT ID NCT05419050
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a drug called denosumab in 15 children aged 4 to 14 with fibrous dysplasia, a rare bone disease that causes weak spots and fractures. The goal was to see if the drug could stop bone lesions from growing during childhood. Participants received injections every 4 weeks for 48 weeks and were monitored with scans and blood tests.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States
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