Polyarteritis nodosa
MONDO:0019170Polyarteritis nodosa (PAN) is a rare, clinically heterogeneous, rheumatologic disease characterized by necrotizing inflammatory lesions affecting small- and medium-sized blood vessels. PAN most commonly affects skin, joints, peripheral nerves, the gut, and the kidney.
Also known as: Küssmaul-Maier disease, PAN, classic polyarteritis nodosa, classical polyarteritis nodosa, panarteritis nodosa, periarteritis nodosa, polyarteritis nodosa, periarteritis
11 clinical trials for this condition and its sub-types.
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Broader categories
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New combo therapy aims to tame rare blood vessel disease
Disease control CompletedThis study tested whether adding azathioprine to standard corticosteroid treatment helps people with certain types of vasculitis (blood vessel inflammation) achieve remission and avoid relapses. 114 newly diagnosed patients without poor prognosis factors took part. The goal was t…
Phase: PHASE3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 26, 2026 16:48 UTC
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Could a tiny dose of naltrexone ease vasculitis symptoms?
Symptom relief CompletedThis study tested whether a low dose (4.5 mg) of naltrexone, a drug already used for alcoholism, can improve physical health and quality of life in people with vasculitis. Sixty participants took either the drug or a placebo daily for six weeks. The goal was to see if the drug le…
Phase: PHASE2 • Sponsor: University of Pennsylvania • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Stitch showdown: which cesarean closure method lowers niche risk?
Knowledge-focused CompletedThis study looked at 366 women having their first planned cesarean section to see if closing the uterine incision with one layer of stitches or two layers affects the chance of developing a uterine niche (a small pocket in the scar). Participants were asked about symptoms like sp…
Phase: NA • Sponsor: Kafrelsheikh University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC