Piriformis syndrome
MONDO:0043320A condition referring to irritation or compression of the proximal sciatic nerve, secondary to contraction of the piriformis muscle. It results in pain in the hip or the back of the leg mimicking disk-related sciatica.
Also known as: piriformis muscle syndrome, piriformis syndrome, Pseudosciatica, deep gluteal syndrome, hip socket neuropathy, muscle syndrome, piriformis, muscle syndromes, piriformis, pelvic outlet syndrome
31 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Laser test could objectively measure nerve pain for first time
Diagnosis CompletedThis study tested whether a diode laser can act as a biomarker to measure neuropathic pain in people with peripheral neuropathy. Researchers compared pain responses to a lidocaine patch versus a placebo patch in 75 participants. The goal was to see if the laser test could disting…
Phase: NA • Sponsor: University of Utah • Aim: Diagnosis
Last updated Jun 27, 2026 12:09 UTC
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Laser or shockwave: which eases piriformis pain best?
Symptom relief CompletedThis study tested two non-drug treatments for piriformis syndrome, a condition where a muscle in the buttock presses on a nerve, causing pain. Seventy adults received either low-level laser therapy or radial shockwave therapy, both combined with exercise, over four weeks. Researc…
Phase: NA • Sponsor: Beni-Suef University • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Which manual therapy eases piriformis pain better? small study pits stretch vs. release
Symptom relief CompletedThis study compared two hands-on treatments—post-facilitation stretch and active release technique—for piriformis syndrome in 40 women aged 25 to 45. Researchers measured pain, disability, quality of life, and hip movement over six weeks. The goal was to see which approach offers…
Phase: NA • Sponsor: Ibadat International University, Islamabad • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Sound waves or needles? small trial pits two piriformis pain fixes Head-to-Head
Symptom relief CompletedThis completed study compared two treatments for piriformis syndrome, a condition causing buttock and leg pain. Forty adults whose pain lasted at least three months were randomly assigned to receive either five sessions of focused sound wave therapy or a single steroid injection.…
Phase: NA • Sponsor: Gulhane Training and Research Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:10 UTC
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Simple hip exercises may ease piriformis pain, small study finds
Symptom relief CompletedThis study looked at whether doing hip abductor strengthening exercises could help people with piriformis syndrome feel less pain and move better. 48 adults with the condition took part. The exercises focused on strengthening muscles that move the leg away from the body. The goal…
Phase: NA • Sponsor: Riphah International University • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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Can special exercises ease piriformis pain? new study investigates
Symptom relief CompletedThis study looked at whether adding a muscle relaxation technique (integrated neuromuscular inhibition) to a standard set of strengthening exercises (McGill program) helps people with piriformis syndrome more than the exercises alone. Fifty-six adults with chronic buttock pain fr…
Phase: NA • Sponsor: Riphah International University • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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Simple back joint maneuver may soothe stubborn hip muscle cramps
Symptom relief CompletedThis study tested whether manually mobilizing the sacroiliac joint (a joint in the lower back) can reduce tension and pain in the piriformis muscle, a deep hip muscle that often cramps. Researchers used physical therapy techniques on 40 adults with lower back or hip pain and musc…
Phase: NA • Sponsor: Charles University, Czech Republic • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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Stretching showdown: which technique eases piriformis pain best?
Symptom relief CompletedThis study tested two stretching techniques—Post-Isometric Relaxation and Post-Facilitation Stretching—in 36 adults with piriformis syndrome, a condition that causes buttock pain and limits hip movement. Participants did the exercises three times a week for four weeks. Researcher…
Phase: NA • Sponsor: University of Faisalabad • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Ultrasound reveals muscle differences in hip pain patients
Knowledge-focused CompletedThis study used ultrasound to measure the thickness of certain hip muscles in 60 adults with hip pain on one side (Greater Trochanteric Pain Syndrome) and compared them to healthy people. The goal was to see if muscle thickness differs between the groups and to check for related …
Sponsor: Ankara Etlik City Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Ultrasound may help doctors better diagnose piriformis syndrome
Knowledge-focused CompletedThis study used ultrasound to measure the thickness of the piriformis muscle and sciatic nerve in 19 people with piriformis syndrome, comparing the painful side to the pain-free side. The goal was to see if ultrasound can help tell whether the pain comes more from muscle or nerve…
Sponsor: Istanbul University - Cerrahpasa • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC