Permanent neonatal diabetes mellitus
MONDO:0100164Permanent neonatal diabetes mellitus (PNDM) is a monogenic form of neonatal diabetes (NDM) characterized by persistent hyperglycemia within the first 12 months of life in general, requiring continuous insulin treatment.
Also known as: PNDM, monogenic diabetes of infancy, developmental delay, epilepsy, and neonatal diabetes, diabetes mellitus, permanent neonatal, diabetes mellitus, permanent neonatal, with neurologic features, diabetes mellitus, permanent, of infancy
30 clinical trials for this condition and its sub-types.
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Broader categories
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Could a wearable sensor replace Finger-Sticks for hospital diabetes care?
Disease control TerminatedThis study tests whether a continuous glucose monitor (CGM) worn on the skin can accurately track blood sugar levels in hospitalized patients with diabetes who have just had major transplant surgery. The CGM measures glucose every 1-5 minutes, and researchers compare its readings…
Phase: NA • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jul 18, 2026 00:00 UTC
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Newborn screening study aims to catch rare diseases at birth
Diagnosis OngoingThis study offers voluntary screening for newborns in North Carolina to detect a wide range of rare health conditions early. Using a small blood sample already collected at birth, the program tests for dozens of disorders, including spinal muscular atrophy, cystic fibrosis, and m…
Sponsor: RTI International • Aim: Diagnosis
Last updated Jul 03, 2026 00:00 UTC
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Blood test could unmask silent heart failure in diabetics
Diagnosis OngoingThis study tests whether a blood test for NT-proBNP can spot undiagnosed heart failure in 706 people with diabetes who are at high risk. Those with elevated levels get a heart ultrasound and exam. The goal is to see if this screening strategy leads to more early diagnoses and pro…
Phase: NA • Sponsor: NHS Greater Glasgow and Clyde • Aim: Diagnosis
Last updated Jun 27, 2026 08:11 UTC
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New study tracks hidden blood sugar index fluctuations in diabetes patients
Knowledge-focused OngoingThis study looks at how a measure called the hemoglobin glycation index (HGI) changes over time in 750 adults with diabetes who use continuous glucose monitors. HGI compares lab-measured blood sugar levels with estimated levels from a glucose monitor. Researchers will collect dat…
Phase: NA • Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:38 UTC
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Diabetes drug linked to Post-Surgery complication? new study investigates
Knowledge-focused OngoingThis observational study tracks 300 adults with diabetes who take SGLT-2 inhibitors and are recovering from surgery in the intensive care unit. Researchers want to find out how often a rare type of diabetic ketoacidosis (called euglycemic DKA) occurs after surgery. The goal is to…
Sponsor: Kocaeli City Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:41 UTC