Parasitic eye infection

This study looked back at medical records of 23 people in Spain who had a rare eye infection called acanthamoeba keratitis. All patients were treated with polihexanide eye drops as part of a special access program. The main goal was to see how many were cured after treatment, wit…

This study looked at the best ways to treat a rare but serious eye infection called acanthamoeba keratitis, which is caused by a parasite. 49 people took part. In the first part, they received either one drug or a combination of two drugs. In the second part, they were given ster…

This study tested whether adding a light-activated dye (rose bengal) to standard antibiotic or antifungal eye drops could improve vision in people with severe corneal infections. About 330 adults in India and Brazil with fungal or amoeba infections received either standard drops …

This study tested whether a drug called moxidectin, combined with other medicines, works better than the standard treatment (ivermectin combinations) for lymphatic filariasis, a parasitic disease that can cause severe swelling. 164 adults with the infection received a single dose…

This massive study tested whether giving deworming medicine (albendazole) to everyone in a community, not just children, can break the cycle of soil-transmitted worm infections. Over 350,000 people in India, Malawi, and Benin took part. The goal was to see if treating entire vill…

This study looked at whether giving hospital-level care to acutely ill adults in their own homes in rural areas works well. 160 people with various conditions like infections, heart failure, or COPD took part. The goal was to see if this approach could lower costs and help patien…

This study looks back at medical records of 40 people with acanthamoeba keratitis, a rare but serious eye infection. All patients received 0.8 mg/ml polihexanide eye drops as part of a compassionate use program. Researchers want to see how many patients were cured, defined as hav…

This study looked at how well a new, quick finger-prick test (LumiraDx CRP) measures CRP levels compared to a standard lab test. CRP is a marker of infection, inflammation, or tissue injury. 79 adults with symptoms of these conditions took part. The goal was to see if the new tes…

This early study tested whether a special PET scan using a radioactive form of vitamin B9 (11C-PABA) can help doctors see infections deep inside the body. Researchers scanned 13 healthy people and patients with known or suspected infections. The goal was to see if this method can…

This study looked at 156 critically ill patients to find out what factors help achieve the right levels of beta-lactam antibiotics in the blood. Researchers collected clinical data and used therapeutic drug monitoring to see which patients reached target concentrations. The goal …