Light-Activated dye shows promise for tough eye infections

NCT ID NCT05110001

First seen Jan 31, 2026 · Last updated May 13, 2026 · Updated 20 times

Summary

This study tested whether adding a rose Bengal dye and green light treatment to standard antibiotic or antifungal eye drops could improve vision in people with severe corneal infections. 330 adults in India and Brazil with fungal, amoeba, or culture-negative ulcers and vision of 20/40 or worse were randomly assigned to get either standard drops alone or drops plus the light therapy. The main goal was to compare vision at 6 months between the two groups.

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Contacts and locations

Locations

  • Aravind Eye Care System

    Madurai, Tamil Nadu, India

  • Federal University of São Paulo

    São Paulo, Brazil

Conditions

Explore the condition pages connected to this study.