Green light and pink dye take on tough eye infections
NCT ID NCT05110001
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether adding a light-activated dye (rose bengal) to standard antibiotic or antifungal eye drops could improve vision in people with severe corneal infections. About 330 adults in India and Brazil with fungal or amoeba infections received either standard drops alone or drops plus the dye-and-light treatment. The main goal was to see which group had better eyesight after six months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Rose Bengal dye activated by green light (photodynamic therapy)
What this could lead to
If successful, this could offer a new way to treat stubborn corneal infections and reduce vision loss without needing stronger drugs.
What could go wrong
This is an early-phase trial with 330 participants; the added light therapy may not improve outcomes over standard drugs alone, and risks include eye irritation or scarring.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Aravind Eye Care System
Madurai, Tamil Nadu, India
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Federal University of São Paulo
São Paulo, Brazil