23 patients treated: new hope for rare eye infection?
NCT ID NCT07195864
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked back at medical records of 23 people in Spain who had a rare eye infection called acanthamoeba keratitis. All patients were treated with polihexanide eye drops as part of a special access program. The main goal was to see how many were cured after treatment, with a follow-up 30 days later.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- polihexanide (PHMB) 0.08% eye drops
- What this could lead to
- If results are positive, this could support the use of polihexanide as a standard treatment for acanthamoeba keratitis, a rare but serious eye infection.
- What could go wrong
- This is a small, retrospective review of only 23 patients, not a controlled trial. Results may not apply to all patients, and the study cannot prove cause and effect.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHUO Ourense
Ourense, Ourense, Spain
-
HU La Paz
Madrid, Madrid, Spain
-
HU Ramon y Cajal
Madrid, Principality of Asturias, Spain
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Hospital la Fé
Valencia, Valencia, 46026, Spain
-
IO Fernandez Vega
Madrid, Madrid, Spain
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