Osteogenesis imperfecta-retinopathy-seizures-intellectual disability syndrome
MONDO:0017196Osteogenesis imperfecta-retinopathy-seizures-intellectual disability syndrome is characterized by osteogenesis imperfecta, wormian bones, optic atrophy, retinopathy, seizures and severe developmental delay. It has been described in two sibs born to consanguineous parents.
Also known as: Al Gazali-Nair syndrome, Al Gazali Sabrinathan Nair syndrome, osteogenesis imperfecta retinopathy seizures intellectual deficit
32 clinical trials for this condition and its sub-types.
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New eye scanner could sharpen diagnosis of glaucoma and retina diseases
Diagnosis CompletedThis study is testing a new eye imaging device called the VG200D, which uses advanced technology to take detailed pictures of the eye. Researchers want to see if it works as well as a standard device for measuring parts of the eye in people with glaucoma, retina problems, corneal…
Sponsor: Intalight, Inc • Aim: Diagnosis
Last updated Jul 31, 2026 00:00 UTC
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Cannabinoid drug tested for aggression in disabled adults
Symptom relief CompletedThis early-phase trial tested the safety of nabilone, a synthetic cannabinoid, in 20 adults with intellectual and developmental disabilities who have severe aggression. The goal was to see if the drug is well-tolerated and to gather initial data on whether it might reduce aggress…
Phase: PHASE1 • Sponsor: Hsiang-Yuan Lin • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Soothing sounds: slow music eases anxiety during eye procedures
Symptom relief CompletedThis study tested whether playing slow tempo music before and during an eye injection (intravitreal injection) can reduce anxiety and pain. 144 adults took part, with half listening to music and the other half receiving standard care. Researchers measured anxiety using saliva tes…
Phase: NA • Sponsor: Ng Yu Siang • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Built-In eye scanner could give surgeons a live 3D view during operations
Knowledge-focused CompletedThis study tests a microscope that has an OCT scanner built directly into it, allowing surgeons to take detailed cross-sectional images of the eye during surgery. The goal is to see if this setup is practical and whether the extra visual information helps guide surgical decisions…
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Aug 05, 2026 00:00 UTC
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New eye scanner aims to sharpen view of retinal disease
Knowledge-focused CompletedThis trial tests a new device called P200TxE that takes detailed images of the back of the eye. Researchers want to see how well it captures images in people with retinal diseases like glaucoma or macular degeneration. The study involves adults aged 22 and older who have been dia…
Phase: NA • Sponsor: Optos, PLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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AI boosts eye Doctors' accuracy in reading retinal scans?
Knowledge-focused CompletedThis study tested whether artificial intelligence (AI) can help doctors detect retinal diseases from ultra-widefield eye images. 462 images were read by four eye doctors with different experience levels, both with and without AI assistance. The goal was to see if AI improves accu…
Sponsor: Xiamen Ophthalmology Center Affiliated to Xiamen University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Paws for thought: cat training program shows promise for youth with disabilities
Knowledge-focused CompletedThis study tested a new program where early adolescents with developmental disabilities learned to train their family cat using positive reinforcement. The goal was to see if the training could improve the cat's attachment to the child and give the child a sense of responsibility…
Phase: NA • Sponsor: Oregon State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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New program aims to boost tech careers for young adults with disabilities
Knowledge-focused CompletedThis study tested a program called TECH-Prep designed to help African American high school students and young adults with developmental disabilities explore careers in technology. The program included training and internships to increase interest in tech jobs, confidence, and rea…
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Which toothbrush works best for kids with special needs? study finds out!
Knowledge-focused CompletedThis study tested whether a triple-headed toothbrush removes more dental plaque than a regular single-headed toothbrush when parents brush the teeth of preschool children with developmental disabilities. Twenty-four children aged 3 to 6 years participated, and each child tried bo…
Phase: NA • Sponsor: Mahidol University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC