Osteochondritis dissecans

MONDO:0017178

A rare bone disease characterized by an acquired idiopathic necrotic lesion of subchondral bone with the formation of a sequestrum, which may detach to form loose bodies in joints. OCD mainly affects the knee, ankle and elbow joints and can lead to pain, functional limitations and secondary osteoarthritis.

Also known as: Koenig disease, Konig disease, König disease, OD, osteochondritis dissecans, osteochondritis dissecans (disease), familial osteochondritis dissecans, SSOAOD

52 clinical trials for this condition and its sub-types.

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Broader categories

Disease (618) Musculoskeletal system disorder (196) Hereditary disease (172) Osteonecrosis (56) Bone disorder (47) Human disease (14) Skeletal system disorder (4) Disease of genetic or genomic mechanism (2) Disease by body system or component (0) Disease by etiologic mechanism (0)

Trials to join now! 25 Not yet recruiting 7 Not yet finished but already full! 9 Completed 10 Terminated 1

Scientists gather leftover surgical tissue to unlock secrets of bone disease

Knowledge-focused Terminated

This study collected bone, cartilage, skin, and fat tissue from 50 patients undergoing surgery at Children's National Medical Center. The goal was to grow cells from these tissues in the lab and analyze them to better understand bone and connective tissue diseases. The study was …

Sponsor: National Institute of Dental and Craniofacial Research (NIDCR) • Aim: Knowledge-focused

Last updated Jun 27, 2026 07:52 UTC

Osteochondritis dissecans

Broader categories

Scientists gather leftover surgical tissue to unlock secrets of bone disease