Onchocerciasis
MONDO:0017137Onchocerciasis is a form of filariasis, caused by the parasitic worm Onchocerca volvulus, transmitted by the black fly. The infection can either be asymptomatic or manifest as an ocular disease (river blindness) with itchy eyes, erythema, photophobia, onchodermatitis or onchocercal skin disease (classified into acute papular, chronic papular, lichenified, atrophic, and depigmentated) and onchocercomas (over bony prominences). Other classic clinical manifestations are ichthyosis-like lesions (''lizard skin'') and ''hanging groin'', which may be associated with lymphadenopathy.
Also known as: Onchocerca volvulus infection, infection by Onchocerca volvulus, onchocerciasis, River blindness, Robles' disease, infection caused by Onchocerca volvulus, onchocercosis
10 clinical trials for this condition and its sub-types.
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AI app aims to help frontline workers diagnose neglected skin diseases
Diagnosis Not yet recruitingThis study tests whether a mobile app using artificial intelligence can help frontline health workers in sub-Saharan Africa better diagnose skin-related neglected tropical diseases, like leprosy and scabies. Researchers will collect images from dermatologists to train the AI, the…
Phase: NA • Sponsor: Kenya Medical Research Institute • Aim: Diagnosis
Last updated Jun 27, 2026 12:04 UTC
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New study aims to bring mental health support to people with neglected skin diseases in ghana
Knowledge-focused Not yet recruitingThis study will test a new way to care for people in Ghana who have both a neglected tropical skin disease (like leprosy or Buruli ulcer) and mental health challenges like depression or anxiety. Researchers will work with 200 affected adults and local health workers to create a G…
Phase: NA • Sponsor: Liverpool School of Tropical Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC