Obesity due to pro-opiomelanocortin deficiency
MONDO:0012335Pro-opiomelanocortin (POMC) deficiency is a form of monogenic obesity resulting in severe early-onset obesity, adrenal insufficiency, red hair and pale skin.
Also known as: POMC Deficiency, POMC deficiency, obesity, adrenal insufficiency, and red hair due to POMC deficiency, OBAIRH, PROOPIOMELANOCORTIN deficiency, obesity, early-onset, adrenal insufficiency, and Red hair, obesity, early-onset, with adrenal insufficiency and RED hair, obesity, early-onset, with adrenal insufficiency and Red hair
56 clinical trials for this condition and its sub-types.
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Sleep more, sugar less? new study tests melatonin and morning light for teens
Disease control Not yet recruitingThis study looks at whether improving sleep habits can help teenagers with overweight or obesity better regulate blood sugar and energy. Researchers will enroll 60 teens aged 14-19 who get less than 7 hours of sleep on school nights. For two weeks, participants will follow a slee…
Phase: NA • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Dieters get secret weapon: metabolic feedback boosts weight loss
Disease control Not yet recruitingThis study looks at whether giving people feedback on their metabolic profile (blood test results) halfway through a 3-month low-starch, low-sugar diet helps them lose more weight. 300 overweight adults (BMI over 25) will follow the diet, and half will learn their metabolic impro…
Phase: NA • Sponsor: Region Skane • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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New Weight-Loss shot enters first human safety trial
Disease control Not yet recruitingThis early-stage study tests an experimental drug called CMS-D008 in 110 healthy and overweight or obese adults. The main goal is to check safety and how the body processes the drug, not weight loss. Participants will receive either the drug or a placebo as injections, and resear…
Phase: PHASE1 • Sponsor: Shenzhen Kangzhe Biotechnology Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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New pain block study aims to cut opioid use after sleeve gastrectomy
Symptom relief Not yet recruitingThis study will compare two ultrasound-guided nerve blocks—the external oblique intercostal plane block and the subcostal transversus abdominis plane block—for controlling pain after laparoscopic sleeve gastrectomy. Ninety adults aged 18–65 will receive one of the blocks plus sta…
Phase: NA • Sponsor: Sanliurfa Education and Research Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Which gas blower hurts less after Weight-Loss surgery?
Symptom relief Not yet recruitingThis study will compare two devices that blow gas into the belly during laparoscopic sleeve gastrectomy (a weight-loss surgery). The goal is to see if one device causes less pain after surgery than the other. About 74 adults aged 22 to 65 having planned sleeve gastrectomy will be…
Phase: NA • Sponsor: SurgiQuest, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Could a smartwatch replace a hospital stay after gastric bypass?
Knowledge-focused Not yet recruitingThis pilot study tests whether patients having laparoscopic gastric bypass can safely go home the same day if they use a remote monitoring device. Forty adults will be randomly assigned to either same-day discharge with remote monitoring or an overnight hospital stay. The study w…
Phase: NA • Sponsor: Jessa Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Study reveals how extra weight changes anesthesia effects
Knowledge-focused Not yet recruitingThis study watches how body fat and muscle affect the way anesthetic drugs work in overweight and obese patients. Researchers will measure body composition and drug levels in 2,100 adults during surgery. The goal is to understand why heavier patients may have more complications, …
Sponsor: Second Affiliated Hospital of Wenzhou Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Can better posture help women move better? new study investigates
Knowledge-focused Not yet recruitingThis observational study will examine how posture habits and body awareness relate to physical function in 80 women aged 18-65 across different BMI categories (normal weight to obesity). Participants will fill out questionnaires and perform simple movement tests. The goal is to u…
Sponsor: Ondokuz Mayıs University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Carbon dioxide during Weight-Loss surgery: does it affect how soon you go home?
Knowledge-focused Not yet recruitingThis study watches how carbon dioxide gas, used to inflate the belly during laparoscopic weight-loss surgery, changes blood bicarbonate levels. Researchers will track 85 adults having sleeve gastrectomy or gastric bypass to see if these changes relate to how long the gas is used …
Sponsor: Istinye University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC