Nephritis
MONDO:0001166Inflammation of renal tissue.
Also known as: inflammation of kidney, kidney inflammation
504 clinical trials for this condition and its sub-types, 16 tagged with Nephritis itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Nephritis
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Glomerulonephritis 33 trials · 457 incl. sub-types
20 sub-types
- Lupus nephritis 140 trials
- IgA glomerulonephritis 123 trials
- Granulomatosis with polyangiitis 95 trials · 115 incl. sub-types Sub-types →
- Membranous glomerulonephritis 70 trials · 78 incl. sub-types Sub-types →
- Lipoid nephrosis 32 trials
- Primary membranoproliferative glomerulonephritis 0 trials · 26 incl. sub-types Sub-types →
- Membranoproliferative glomerulonephritis 11 trials
- Pauci-immune glomerulonephritis 1 trial · 5 incl. sub-types Sub-types →
- Rapidly progressive glomerulonephritis 3 trials · 4 incl. sub-types Sub-types →
- Proliferative glomerulonephritis 1 trial · 2 incl. sub-types Sub-types →
- Anti-basement membrane glomerulonephritis 1 trial
- Immunotactoid glomerulopathy 1 trial
- Acute poststreptococcal glomerulonephritis 0 trials
- Autoimmune glomerulonephritis 0 trials
- Diffuse glomerulonephritis 0 trials Sub-types →
- Exudative glomerulonephritis 0 trials
- Focal embolic glomerulonephritis 0 trials
- Immune-complex glomerulonephritis 0 trials
- Mesangial proliferative glomerulonephritis 0 trials
- Subacute glomerulonephritis 0 trials
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Hereditary nephritis 17 trials · 152 incl. sub-types
7 sub-types
- IgA glomerulonephritis 123 trials
- Alport syndrome 17 trials · 18 incl. sub-types Sub-types →
- Immunoglobulin-mediated membranoproliferative glomerulonephritis 12 trials
- C3 glomerulonephritis 7 trials
- Karyomegalic interstitial nephritis 2 trials
- Balkan nephropathy 1 trial
- Complement factor H deficiency 0 trials Sub-types →
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Pyelitis 0 trials · 21 incl. sub-types
3 sub-types
- Pyelonephritis 8 trials · 21 incl. sub-types Sub-types →
- Pyelocystitis 0 trials
- Pyeloureteritis cystica 0 trials
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Interstitial nephritis 6 trials · 9 incl. sub-types
2 sub-types
- Karyomegalic interstitial nephritis 2 trials
- Balkan nephropathy 1 trial
Most studied deeper sub-types
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Gene therapy breakthrough targets kidney disease in High-Risk patients
Disease control Recruiting nowThis study tests a new gene therapy, PS-002, for adults with IgA nephropathy, a kidney disease that can lead to kidney failure. The therapy aims to control the disease in people who are at high risk of getting worse despite current treatments. Participants receive a single dose a…
Phase 1/2 • Sponsor: Purespring Therapeutics Limited • Aim: Disease control
Last updated Sep 11, 2026 00:00 UTC
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New hope for kidney disease: JADE101 trial launches
Disease control Recruiting nowThis study tests a new drug, JADE101, in 30 adults with IgA nephropathy, a kidney disease. The goal is to see if the drug is safe and can reduce protein in the urine, a sign of kidney damage. Participants must be on stable standard care and have a kidney biopsy confirming the dis…
Phase 2 • Sponsor: Jade Biosciences, Inc. • Aim: Disease control
Last updated Aug 22, 2026 00:00 UTC
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New hope for kidney disease: Zigakibart's Long-Term safety under study
Disease control Recruiting nowThis study looks at the long-term safety of a drug called zigakibart for adults with IgA nephropathy, a kidney disease. It is for people who have already finished a previous zigakibart study. Researchers will monitor side effects and check kidney function over 96 weeks.
Phase 3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Aug 19, 2026 00:00 UTC
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New drug aims to calm immune attacks on kidneys
Disease control Recruiting nowThis Phase 2 study tests atacicept, a drug that may reduce immune system attacks on the kidneys. About 250 adults with various autoimmune kidney diseases (like IgA nephropathy or membranous nephropathy) will receive weekly injections. Researchers will check safety and measure cha…
Phase 2 • Sponsor: Vera Therapeutics, Inc. • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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New gel could outperform standard therapy for kidney disease
Disease control Recruiting nowThis Phase 3 trial is testing a new gel called SNP-ACTH (1-39) against the standard drug rituximab in 148 adults with primary membranous nephropathy, a rare kidney condition. The goal is to see if the gel can better reduce protein in the urine and protect kidney function over 24 …
Phase 3 • Sponsor: Cerium Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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New drug BHV-1400 tested for kidney disease
Disease control Recruiting nowThis early-stage trial tests whether BHV-1400 is safe and tolerable for people with IgA nephropathy, a kidney disease. About 20 participants with confirmed IgA nephropathy will receive the drug subcutaneously. The main goal is to check for side effects and lab abnormalities.
Phase 1 • Sponsor: Biohaven Therapeutics Ltd. • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Lupus drug may harm ovaries – could a hormone shot help?
Knowledge-focused Recruiting nowThis study surveys women under 40 with lupus who are starting cyclophosphamide, a drug that can damage ovaries and cause infertility. Some received an additional drug called GnRHa to protect their ovaries. Researchers will compare menstrual health and fertility between those who …
Sponsor: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) • Aim: Knowledge-focused
Last updated Aug 06, 2026 00:00 UTC
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New ultrasound technique could spare kidney patients from biopsies
Knowledge-focused Recruiting nowThis study is testing a new ultrasound method to look at tiny blood vessels in the kidneys of people with nephritis (kidney inflammation). Researchers will use contrast-enhanced ultrasound and ultrasound localization microscopy to create detailed images of kidney blood flow. The …
Sponsor: University of Erlangen-Nürnberg Medical School • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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New study peers inside the heart and kidneys of people with type 1 diabetes
Knowledge-focused Recruiting nowThis observational study will use special PET scans to measure how much oxygen the heart and kidneys use in people with type 1 diabetes. Researchers want to see if a more intensive treatment plan (multifactorial intervention) lowers oxygen demand compared to standard care. Forty …
Sponsor: University of Aarhus • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC