Nasopharyngitis

This phase 3 trial tests whether Jinhua Qinggan Granules, a traditional Chinese herbal medicine, can eliminate symptoms of acute upper respiratory infections (like fever, sore throat, and congestion) within three days. About 273 adults with early-stage cold or flu will receive ei…

This study tested whether a special infant formula containing lactoferrin and human milk oligosaccharides (HMOs) could improve immunity in newborns. 240 healthy full-term babies were randomly assigned to receive either the test formula, a standard formula, or breast milk for 12 m…

This study tested whether the drug vapendavir can reduce breathing problems in people with COPD who catch a rhinovirus (common cold). Fifty-two adults with COPD were given either vapendavir or a placebo after being exposed to the virus. The main goal was to see if vapendavir lowe…

This study tested whether giving families educational materials, alcohol-based hand sanitizers, and surgical face masks could reduce the spread of colds and flu among household members. Researchers followed 2,788 people in 450 households in Northern Manhattan for 15 months. They …

This study is testing a hypertonic seawater aerosol spray (a saltwater mist) to see if it helps relieve nasal symptoms, improve sleep, and thin mucus in people with colds, sinus infections, or similar upper respiratory infections. About 110 adults and children aged 2 and older wi…

This study looked at whether taking a probiotic called LP28 can help older adults fight off colds and feel better. 102 people who had at least two colds in the past year took part. Researchers measured cold symptoms and immune cell levels to see if the probiotic made a difference…

This completed study looked at how two different Robitussin cough syrup regimens affect quality of life in 244 adults with coughs from the common cold. One group used a single daytime/nighttime syrup, while the other used separate daytime and nighttime syrups. Researchers measure…

This Phase 3 trial tested whether a single pill containing paracetamol (pain reliever/fever reducer), fexofenadine (antihistamine), and phenylephrine (decongestant) works better than a placebo for treating cold and flu symptoms. 567 adults in Brazil took the combo pill or a place…

This study looks at how regular winter swimming—bathing in cold open water during winter—affects blood cells, blood flow, and stress-fighting enzymes in healthy men. Researchers compare winter swimmers to a control group who never swim in cold water and have a sedentary lifestyle…

This study tested a drug called suzetrigine, which blocks a specific nerve channel (NaV1.8) involved in pain signaling. In 67 healthy volunteers, tiny amounts were injected into the skin alongside a placebo and lidocaine. Participants received six different types of brief pain (e…

This completed study looked at whether substances in nasal fluid can help doctors objectively measure the severity of respiratory conditions like asthma, COPD, hayfever, and sinusitis. Researchers collected samples from 111 adults (including healthy volunteers) using a small nasa…