Myotonic dystrophy type 1
MONDO:0008056Steinert disease, also known as myotonic dystrophy type 1, is a muscle disease characterized by myotonia and by multiorgan damage that combines various degrees of muscle weakness, arrhythmia and/or cardiac conduction disorders, cataract, endocrine damage, sleep disorders and baldness.
Also known as: DM1, DMPK myotonic dystrophy, MD1, Myotonic Dystrophy, Steinert disease, Steinert myotonic dystrophy syndrome, Steinert syndrome, dystrophia myotonica
56 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
-
Could a common blood pressure pill ease muscle stiffness? early trial launches
Symptom relief Not yet recruitingThis early-stage trial tests amlodipine, a calcium channel blocker used for high blood pressure, in 20 adults with myotonic dystrophy type 1. The goal is to see if the drug is safe and can improve muscle strength, reduce stiffness, and help with daily function. All participants w…
Phase: PHASE1 • Sponsor: University of Rochester • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
-
Can watching the course of myotonic dystrophy unlock better care?
Knowledge-focused Not yet recruitingThis study follows 100 adults with myotonic dystrophy (types 1 or 2) for two years to understand how muscle stiffness, daily function, and heart health change over time. Researchers will look back at up to 18 months of past medical records and then track participants with clinic …
Sponsor: Lupin Ltd. • Aim: Knowledge-focused
Last updated Jul 30, 2026 00:00 UTC