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Myositis ossificans

MONDO:0003964

A disorder characterized by non-neoplastic bone formation in soft tissues. It usually follows blunt trauma and bleeding in the deep soft tissues.

Also known as: FOP, myositis ossificans progressiva, progressive myositis ossificans, progressive ossifying myositis, fibrodysplasia ossificans progressiva

12 clinical trials for this condition and its sub-types.

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Sub-types

Traumatic myositis ossificans (0)

Broader categories

Disease (680) Inflammatory disease (332) Musculoskeletal system disorder (207) Myositis disease (98) Muscle tissue disorder (56) Human disease (14) Myopathy (14) Skeletal muscle disorder (10) Disease by body system or component (0) Disease by developmental or physiological process (0)

Trials to join now! 6 Not yet recruiting 1 Not yet finished but already full! 4 Terminated 1

Experimental pill aims to stop extra bone growth in rare disease

Disease control Terminated

This phase 2 trial tested two doses of an oral drug called fidrisertib (IPN60130) in children and adults with fibrodysplasia ossificans progressiva (FOP), a rare condition where soft tissues turn into bone. The goal was to see if the drug could reduce new abnormal bone growth com…

Phase: PHASE2 • Sponsor: Clementia Pharmaceuticals Inc. • Aim: Disease control

Last updated Jun 27, 2026 12:23 UTC