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Myositis ossificans

MONDO:0003964

A disorder characterized by non-neoplastic bone formation in soft tissues. It usually follows blunt trauma and bleeding in the deep soft tissues.

Also known as: FOP, myositis ossificans progressiva, progressive myositis ossificans, progressive ossifying myositis, fibrodysplasia ossificans progressiva

12 clinical trials for this condition and its sub-types.

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Sub-types

Traumatic myositis ossificans (0)

Broader categories

Disease (680) Inflammatory disease (332) Musculoskeletal system disorder (207) Myositis disease (98) Muscle tissue disorder (56) Human disease (14) Myopathy (14) Skeletal muscle disorder (10) Disease by body system or component (0) Disease by developmental or physiological process (0)

Trials to join now! 6 Not yet recruiting 1 Not yet finished but already full! 4 Terminated 1

Promising antibody trial aims to halt rare bone disease in kids

Disease control Not yet recruiting

This Phase 3 trial tests garetosmab, an antibody that blocks activin A, in 18 children and teens with fibrodysplasia ossificans progressiva (FOP), a rare disease where muscle and tissue turn into bone. The study will check safety, side effects, and whether the drug reduces new ab…

Phase: PHASE3 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control

Last updated Jun 27, 2026 12:26 UTC