Moyamoya disease

This study tests a metaverse-based surgical platform that uses extended reality (XR) to help surgeons precisely locate blood vessels during brain bypass surgery. The trial includes 30 adults with moyamoya disease or chronic cerebral ischemia who need an extracranial-intracranial …

This study tests a personalized approach to managing fluids during brain surgery for children with Moyamoya disease. Instead of standard blood pressure targets, doctors will use each child's baseline heart function to guide fluid delivery. The goal is to reduce temporary stroke-l…

This study tests a new robotic surgical system (Symani) in 15 adults with Moyamoya disease, a rare condition that narrows brain arteries and raises stroke risk. The surgery aims to improve blood flow to the brain. Participants must have mild to moderate symptoms and agree to the …

This early-phase trial tests a new treatment for Moyamoya disease, a rare condition where major brain arteries narrow, raising stroke risk. The treatment combines a special muscle flap with injections of tiny particles from stem cells (iPSC-EVs) to encourage new blood vessel grow…

This study is testing a new type of MRI scan called eASL that measures blood flow in the brain without needing a contrast injection. It will include 50 children with conditions like Moya-moya or sickle cell disease that affect brain arteries. The goal is to see if eASL gives clea…

This study explores whether a training program that mixes cognitive tasks (like memory and attention exercises) with physical therapy can improve recovery in people with post-stroke cognitive impairment or Moyamoya disease. Researchers will also use brain imaging to see how think…

This small study tests a smartphone app that creates a 'digital twin' of the patient to help manage health after a stroke, moyamoya disease, or cerebral amyloid angiopathy. Twenty adults will either use the app plus standard care, or standard care alone. The goal is to see if pat…

This study is developing a model to predict the risk of brain hemorrhage in people with moyamoya disease, a condition where brain arteries become blocked and fragile. The researchers will use ultra-high-field 5T MRI to see fine details of blood vessels and analyze blood and urine…

This study tests two methods of giving the anesthetic remimazolam during cerebrovascular bypass surgery in people with moyamoya disease. One method uses a computer-controlled pump (TCI), the other uses manual weight-based dosing. The goal is to see which approach uses less total …

This study is looking at families where someone has moyamoya disease, a rare condition that narrows brain arteries and raises stroke risk. Researchers want to find early warning signs in first-degree relatives using advanced MRI scans and biological samples like blood and saliva.…

This study is gathering information from 4500 people who have or will have brain surgery for conditions like aneurysms, tumors, epilepsy, and Parkinson's disease. The goal is to find patterns that help doctors predict how well someone will recover. By standardizing how outcomes a…