New MRI technique could sharpen brain imaging in kids with clogged arteries

NCT ID NCT05026060

Recruiting now Diagnosis Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 2 times

Summary

This study is testing a new type of MRI scan called eASL that measures blood flow in the brain without needing a contrast injection. It will include 50 children with conditions like Moya-moya or sickle cell disease that affect brain arteries. The goal is to see if eASL gives clearer, more reliable images than the standard ASL method currently used.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: eASL sequence (an MRI technique without contrast dye)
What this could lead to: If successful, this could provide a safer, more accurate way to measure brain blood flow in children with arterial disease, helping guide treatment decisions.
What could go wrong: This is a small, early-stage study (50 children) testing a new imaging method, not a treatment. It may not prove better than current methods or may be impractical in routine care.

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Conditions

The condition(s) this trial relates to.

arterial disorder cerebral arterial disease cerebral infarction Moyamoya disease sickle cell disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CEREBRAL ARTERIOPATHY

Contacts and locations

Locations

Hôpital Necker-Enfants Malades
RECRUITING

Paris, 75015, France

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