Can a daily pill and a simple physical therapy delay moyamoya strokes?

NCT ID NCT07762547

First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This trial tests whether aspirin and a non-invasive physical therapy called ischemic conditioning can slow the progression of moyamoya disease, a rare brain vessel disorder that can cause strokes and cognitive decline. The study enrolls adults with moyamoya disease or syndrome who have not had a major stroke, and compares these treatments against placebos over one year. The goal is to see if these approaches can prevent disease progression and reduce the risk of cerebrovascular events like transient ischemic attacks and strokes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
aspirin and remote ischemic conditioning
What this could lead to
If effective, this could establish a non-surgical treatment to slow moyamoya disease and reduce stroke risk, offering an alternative for patients who cannot or prefer not to have surgery.
What could go wrong
The trial is early and results are not yet known. Aspirin may increase bleeding risk, and ischemic conditioning may not provide benefit in this specific condition.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing Tiantan Hospital, Capital Medical University

    Beijing, Beijing Municipality, 100000, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.