Monogenic diabetes

This study tested whether adding a smartphone app with short videos on mental health, diet, exercise, and insulin adjustment to standard care could improve blood sugar control and birth weight in pregnant women with diabetes. Over 600 women participated. The goal was to see if th…

This study followed 30 adults with type 1 diabetes who used the Smartguard system, a partially automated insulin pump that can pause insulin delivery when it predicts a low blood sugar. The goal was to see how well the system works in everyday life, focusing on time spent in the …

This study looked at two different ways to manage blood sugar in pregnant women with MODY2 diabetes, a genetic condition that affects insulin release. The goal was to see if using ultrasound to guide insulin treatment could prevent the baby from growing too large. 46 women took p…

This study tested whether babies with a rare, permanent form of diabetes caused by specific gene changes could switch from daily insulin injections to an oral pill called glibenclamide. Nineteen infants took part. The goal was to see if the pill could control their blood sugar an…

This study tested a new liquid version of the diabetes drug glibenclamide in 10 children with neonatal diabetes. The goal was to see if the liquid form is easier to take and as safe as the standard pills. Children first took the pill form for one month, then switched to the liqui…

This trial tests whether a quick cold spray on the skin before a subcutaneous insulin injection can reduce pain compared to a placebo spray. Adults in the emergency department who need at least two insulin injections receive both sprays in random order, rating their pain after ea…

This study tested custom-made insoles for people with diabetic foot to see if they improve balance and walking. Twenty-five participants aged 40 to 65 with early-stage diabetic foot issues were included. The insoles were designed using pressure measurements to offload high-pressu…

This study explored how family members share health information about genetic diseases like sickle cell, diabetes, and cancer. Over 1,000 adults completed surveys or interviews about their family health history and support. The goal was to understand social and relational factors…

This completed study looked for rare, single-gene causes of insulin-dependent diabetes in 127 participants. Researchers collected blood samples and performed metabolic tests to identify genetic defects. The goal was to better understand these genetic forms of diabetes and possibl…

This study tested whether special communication training for pharmacists and general practitioners helps them involve older patients in decisions to stop or lower medications for heart disease and diabetes. Researchers enrolled 310 patients aged 75 and older who were taking certa…

This study tested whether taking acetaminophen (like Tylenol) interferes with a new continuous glucose monitor called Biolinq. Thirty-one adults with diabetes wore the Biolinq sensor and a standard CGM for three days. On day three, they took acetaminophen and researchers compared…

This completed study looked at how diet and exercise change blood sugar levels in 61 adults with diabetes. Researchers used advanced tests (genomics, proteomics, etc.) to understand the body's complex response. The goal is to build a tool that helps doctors personalize diabetes c…