Lyme disease
MONDO:0019632Lyme disease (named after the towns in the USA where the disease was first identified) is a bacterial infection caused by Borrelia burgdorferi.
Also known as: Borrelia, Borrelia burgdorferi infection, Borreliella burgdorferi caused disease or disorder, Borreliella burgdorferi disease or disorder, Borreliella burgdorferi infectious disease, Lyme borreliosis, Lyme disease
30 clinical trials for this condition and its sub-types.
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New mRNA vaccine could stop lyme disease in its tracks
⭐️ VACCINE ⭐️ OngoingThis study tests an experimental mRNA vaccine (mRNA-1982) designed to prevent Lyme disease, which is spread by tick bites. About 350 healthy adults aged 18 to 70 will receive either the vaccine or a placebo to check for safety and immune response. The goal is to find the best dos…
Phase: PHASE2 • Sponsor: ModernaTX, Inc. • Aim: ⭐️ VACCINE ⭐️
Last updated Aug 05, 2026 00:00 UTC
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Promising lyme vaccine moves to final testing phase
⭐️ VACCINE ⭐️ OngoingThis study tests a new Lyme disease vaccine (VLA15) in about 200 healthy adults aged 18 to 44. Participants receive five shots over two years—four of the vaccine and one of salt water—to see if different timing schedules are safe and produce a strong immune response. The goal is …
Phase: PHASE3 • Sponsor: Pfizer • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 12:29 UTC
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Could a single pill stop lyme disease before it starts?
Prevention OngoingThis study tests a new pill called TP-05 (lotilaner) to see if it can prevent Lyme disease in healthy adults who are often around ticks. The pill is already used in pets to kill ticks. Researchers will give either a low dose, high dose, or placebo to 700 volunteers and watch for …
Phase: PHASE2 • Sponsor: Tarsus Pharmaceuticals, Inc. • Aim: Prevention
Last updated Jul 11, 2026 00:00 UTC