Local anesthetic poisoning

This study tested whether adding dexmedetomidine or dexamethasone to a local anesthetic mixture improves pain control and patient satisfaction during cataract surgery. 75 adults undergoing eye surgery received one of the two additives or a placebo. The main goal was to see how lo…

This study looked at whether adding magnesium sulfate to a standard numbing medicine (bupivacaine) in a nerve block could improve pain control after a mastectomy. Seventy women having breast cancer surgery received either the standard nerve block or one with added magnesium. The …

This study tested whether a nerve block (fascia iliaca block) given before spinal anesthesia helps patients with hip or upper thigh fractures get into a comfortable position. Forty patients were randomly assigned to receive either the nerve block with bupivacaine or a placebo (sa…

This study tested two numbing medicines for children's eye exams: a gel (chloroprocaine) and eye drops (oxybuprocaine). 74 children aged 0-17 received one of the two before their eye exam. Researchers checked how well each numbed the eye and if there were any side effects.

This study tested two different numbing creams to see which one works better for pain during a laser skin treatment. 22 adults with sun-damaged skin tried both creams on different sides of their face. The goal was to find which cream provides better pain relief and fewer side eff…

This study tested whether putting lignocaine (a numbing medicine) inside the abdomen during gynecologic open surgery can reduce pain afterward. 112 women having surgery like hysterectomy or cystectomy took part. The goal was to see if this approach lowers pain scores and the need…

This study looked at how the body processes ropivacaine, a numbing medicine, when given as a nerve block for chest surgery. Twenty adults having robotic or video-assisted chest surgery received the block, and researchers measured drug levels in their blood to check for toxicity. …