Leukoplakia
MONDO:0043243A white patch or plaque on a mucous membrane that cannot be characterized clinically or pathologically as any other disease. The diagnosis of leukoplakia is one of exclusion; other conditions such as candidiasis, lichen planus, leukoedema, etc., must be ruled out before a diagnosis of leukoplakia can be made. Leukoplakia may be a premalignant condition.
Also known as: keratotic plaque, leukoplakia, lesion, leukoplakic, lesions, leukoplakic, leukokeratoses, leukokeratosis, leukoplakias, leukoplakic lesion
34 clinical trials for this condition and its sub-types.
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Broader categories
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Electric probe could spot mouth cancer without a biopsy
Diagnosis CompletedThis study tested a custom device that measures electrical impedance (how tissues resist electric current) in mouth lesions. Researchers enrolled 114 people with suspected oral cancer to see if the device could tell the difference between normal, benign, precancerous, and cancero…
Sponsor: Ryan J. Halter • Aim: Diagnosis
Last updated Jun 27, 2026 07:51 UTC
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Could a seed protein stop oral cancer? early study hints at promise
Knowledge-focused CompletedThis early-phase study looked at whether a protein from the Maackia amurensis seed (MASL) can target a receptor called podoplanin found on oral cancer and precancerous cells. Researchers measured how much of this receptor was present in tissue samples from 18 adults with suspicio…
Phase: EARLY_PHASE1 • Sponsor: Rowan University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Saliva secrets: could proteins tell two mouth diseases apart?
Knowledge-focused CompletedThis study looked at saliva from 21 people: some with oral lichen planus, some with oral leukoplakia, and some healthy. The goal was to see if proteins in saliva are different between these groups. Researchers hope these protein differences could one day help doctors tell these t…
Sponsor: Kocaeli University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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New study tests Camera-Only diagnosis for vocal cord problems
Knowledge-focused CompletedThis study looked at 100 adults with irregular patches on their vocal cords. Researchers used a special camera called a laryngostroboscope to see how the vocal cords vibrate, then compared those results with standard tissue analysis. The goal was to see if the camera test alone c…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC