Electric probe could spot mouth cancer without a biopsy

NCT ID NCT05430477

Completed Diagnosis Sponsor: Ryan J. Halter Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested a custom device that measures electrical impedance (how tissues resist electric current) in mouth lesions. Researchers enrolled 114 people with suspected oral cancer to see if the device could tell the difference between normal, benign, precancerous, and cancerous tissue. The goal was to create a database of measurements and images to improve future diagnosis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Electrical impedance imaging device (EII probe)
What this could lead to: If successful, this device could help doctors quickly identify which mouth lesions are cancerous without needing a biopsy.
What could go wrong: This is an early, completed study focused on data collection, not treatment. The device may not prove accurate enough for routine use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

benign neoplasm of oral cavity lip and oral cavity carcinoma oral mucosa leukoplakia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ORAL LESION

Contacts and locations

Locations

Dartmouth-Hitchcock Medical Center

Lebanon, New Hampshire, 03756, United States

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