Legius syndrome
MONDO:0012669Legius syndrome, also known as NF1-like syndrome, is a rare, genetic skin pigmentation disorder characterized by multiple cafC)-au-lait macules with or without axillary or inguinal freckling.
Also known as: Legius syndrome, NF1-like syndrome, neurofibromatosis 1-like syndrome, neurofibromatosis type 1 like syndrome, neurofibromatosis type 1-like syndrome
14 clinical trials for this condition and its sub-types.
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New serums take on hydroquinone in skin brightening showdown
Symptom relief CompletedThis 4-week pilot study tested two brightening serums against 4% hydroquinone in 18 adults with hyperpigmentation or melasma. Each participant used different products on each side of their face to compare results. The goal was to see if the serums could improve skin tone evenness…
Phase: NA • Sponsor: Revision Skincare • Aim: Symptom relief
Last updated Jun 27, 2026 13:06 UTC
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Gene hunt aims to unlock NF1's mysteries
Knowledge-focused CompletedThis study looks at people with neurofibromatosis type 1 (NF1) and their families to find out why some have more severe symptoms than others. Researchers will collect medical history, blood samples, and images to study genes and physical traits. The goal is to identify genes that…
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Aug 09, 2026 00:00 UTC