Joint laxity, familial
MONDO:0007842A type of Ehlers-Danlos syndrome characterized by generalized joint hypermobility often complicated by dislocation of major joints, particularly the shoulder but in some cases the kneecap. Congenital hip dislocation has also been frequently reported. The syndrome has been described in several families. It is transmitted as an autosomal dominant trait, with high penetrance.
Also known as: EDS XI, Ehlers-Danlos syndrome type 11, formerly, Joint instability syndrome, familial joint instability syndrome, familial joint laxity, joint laxity, familial, EDS 11 (formerly), EDS Xi
14 clinical trials for this condition and its sub-types.
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Pilates during pregnancy may speed up postpartum recovery
Disease control CompletedThis study tested whether a structured Pilates program during pregnancy, continued until childbirth, helps women recover ligament strength and reduce pain after giving birth. Researchers followed 42 women at 6 weeks postpartum, measuring joint looseness and activity limitations. …
Sponsor: Ankara Medipol University • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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New foot training shows promise for ankle sprain relief in athletes
Symptom relief CompletedThis study looked at whether a program called Hyperarch Fascia Training (HFT) can reduce ankle pain and improve jumping ability in active adults aged 20-45 who have had ankle sprains. 62 participants were split into two groups: one did HFT exercises remotely for 12 weeks, while t…
Phase: NA • Sponsor: Applied Science & Performance Institute • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Exercise eases shoulder fatigue in new study
Symptom relief CompletedThis study tested whether a supervised exercise program (MoveUS) could reduce fatigue and improve quality of life in 108 adults with shoulder instability. Participants were randomly assigned to either the exercise program or usual care. The results will help determine if this app…
Phase: NA • Sponsor: University of Malaga • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Women's knee injury risk: new study probes hormone link
Knowledge-focused CompletedThis study looked at how hormones and birth control pills affect knee ligament looseness in healthy women. Researchers measured knee laxity in 45 women at two points in their menstrual cycle, comparing those on hormonal contraceptives to those not. The goal was to better understa…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Gene sequencing uncovers mysterious fetal malformations
Knowledge-focused CompletedThis study tested whether a powerful DNA test called high-throughput exome sequencing can find genetic causes of multiple birth defects in fetuses when standard exams fail. Researchers studied 100 fetuses with at least two malformations and no prior diagnosis. They compared the n…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Speedy gene test aims to give answers on birth defects in just 7 days
Knowledge-focused CompletedThis study tested whether a fast type of genetic test called rapid genome sequencing can find the cause of birth defects seen on ultrasound more quickly than current methods. Researchers included 184 pregnancies with certain ultrasound findings. The goal was to see if results cou…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Can flat feet or knock knees affect how kids move? new study investigates
Knowledge-focused CompletedThis completed study looked at 151 children with common postural conditions like flat feet, knock knees, or scoliosis. Researchers used wearable motion sensors and clinical tests to measure balance and motor control, then compared the results to healthy children. The goal was to …
Phase: NA • Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC