Inherited primary ovarian failure
MONDO:0019852An instance of primary ovarian failure that is caused by an inherited modification of the individual's genome.
Also known as: hereditary primary ovarian failure, inherited POI, inherited premature ovarian failure, inherited primary ovarian insufficiency, non-acquired premature ovarian failure
111 clinical trials for this condition and its sub-types.
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Broader categories
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Continued EryDex treatment studied in rare neurological disorder
Disease control TerminatedThis study offered continued treatment with EryDex to 101 people with ataxia telangiectasia (A-T) who had finished a previous trial. The main goal was to monitor safety, including side effects and serious events. The study was terminated early, and it did not aim to cure the dise…
Phase: PHASE3 • Sponsor: Quince Therapeutics S.p.A. • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New IVF drug trial halted early: did it help embryo growth?
Disease control TerminatedThis early-stage trial tested whether adding the drug FE999302 to standard IVF hormones could increase the number of high-quality embryos in women undergoing fertility treatment. The study enrolled 310 women aged 18–40 with specific hormone levels. The trial was terminated early,…
Phase: PHASE1 • Sponsor: Ferring Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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Timing of fertility drug may affect egg quality in IVF
Disease control TerminatedThis early-phase study looked at whether giving an extra fertility drug (FE 999302) at different times during ovarian stimulation could improve the number of good-quality embryos in women undergoing IVF. The trial included 106 women with high ovarian reserve and was stopped early…
Phase: PHASE1 • Sponsor: Ferring Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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Experimental drug shows promise for rare genetic disorder
Disease control TerminatedThis Phase II trial tested a drug called N-Acetyl-L-Leucine (IB1001) in 17 people with Ataxia-Telangiectasia, a rare genetic disease that affects movement and immunity. The study aimed to see if the drug could improve symptoms and slow the disease over time. The trial was termina…
Phase: PHASE2 • Sponsor: IntraBio Inc • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Does Dad's smoking harm fertility? new study investigates
Knowledge-focused TerminatedThis study looked at how a man's smoking habits might affect a couple's ability to have a baby. Researchers compared fertile and infertile couples, measuring smoking markers like carbon monoxide and cotinine in blood, semen, and hair. The goal was to understand if smoking damages…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC