Inflammation of heart layer
MONDO:0024636An inflammatory disease involving a pathogenic inflammatory response in the heart layer.
Also known as: carditis, heart layer inflammation
287 clinical trials for this condition and its sub-types.
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Broader categories
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Shorter antibiotic course after heart surgery for IV drug users shows promise
Disease control TerminatedThis study looked at whether people who had heart surgery for endocarditis (a serious heart infection) related to IV drug use could safely switch from IV antibiotics to oral pills after just two weeks. The goal was to see if this shorter hospital stay was safe and effective. The …
Phase: PHASE4 • Sponsor: West Virginia University • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Heart drug tested to fight COVID-19 complications
Disease control TerminatedThis study tested a drug called CardiolRx in 90 hospitalized COVID-19 patients who also had heart disease or risk factors like diabetes or high blood pressure. The goal was to see if the drug could lower the chance of death, needing intensive care, or having heart problems. The t…
Phase: PHASE2, PHASE3 • Sponsor: Cardiol Therapeutics Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Blood filter during heart bypass may prevent organ damage, but trial stopped early
Disease control TerminatedThis study tested a device called Efferon LPS that filters blood during heart surgery when a heart-lung machine is used. The goal was to see if it could prevent multiple organ failure, especially kidney damage. Only 14 people took part before the study was stopped, so the results…
Phase: NA • Sponsor: Efferon JSC • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Can a PET scan spot silent heart danger from cancer drugs?
Diagnosis TerminatedThis pilot study tested whether a special PET scan (FDG-PET/CT) can detect hidden heart inflammation in cancer patients receiving immune checkpoint inhibitors (ICIs). The goal was to catch this inflammation early, before it becomes severe. Only 2 participants were enrolled, and t…
Sponsor: Mayo Clinic • Aim: Diagnosis
Last updated Jun 27, 2026 12:31 UTC
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Exercise and diet boost mental health in heart infection patients
Symptom relief TerminatedThis study tested whether adding physical rehabilitation and personalized nutrition to standard care helps patients with infective endocarditis (a serious heart infection) feel better during their hospital stay. The goal was to improve mental health and quality of life. The study…
Phase: NA • Sponsor: Johannes Grand • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Heart surgery recovery: can patients manage their own precautions?
Symptom relief TerminatedThis study looked at whether letting patients manage their own recovery precautions after heart surgery leads to a better quality of life compared to following standard sternal precautions. Ten adults who had heart surgery were followed for up to a year. Researchers checked pain,…
Phase: NA • Sponsor: University of Chicago • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Painkiller showdown: which is safer for the heart?
Knowledge-focused TerminatedThis study looked at how two common pain relievers—celecoxib (a Coxib) and naproxen (an NSAID)—affect blood clotting in people with rheumatoid arthritis who also have heart disease or are at high risk for it. All participants took low-dose aspirin daily. The goal was to see if on…
Phase: PHASE4 • Sponsor: Platelet and Thrombosis Research, LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC