Idiopathic achalasia

This study compared two procedures for treating achalasia, a condition where the esophagus doesn't relax properly. One is a balloon dilation (pneumodilation) and the other is a surgery called POEM done through a scope. 132 adults with achalasia were randomly assigned to one treat…

This study tested whether tranexamic acid, a drug that helps blood clot, can lower the chance of infection after gastrointestinal surgery. Over 3,300 adults at higher risk for complications took part. The goal was to see if the drug reduces surgical site infections compared to a …

This study tested a 12-week online mind-body program for adults with chronic conditions like heart failure, cancer, and liver disease. The program included mindful movement, meditation, breathwork, and coping skills. Researchers measured changes in anxiety, depression, fatigue, a…

This study tested whether giving a small amount of s-ketamine during chest surgery could reduce the risk of postoperative delirium (sudden confusion) in patients aged 60 and older. Over 500 participants were randomly assigned to receive either s-ketamine or another drug (dexmedet…

This study tested whether injecting botulinum toxin (like Botox) into the lower esophagus can ease symptoms of nutcracker esophagus, a condition that causes chest pain and trouble swallowing. Twenty-four adults received either the toxin or a placebo in a double-blind setup. The m…

This study looked at 38 people with achalasia cardia, a condition where the esophagus muscle doesn't relax, making swallowing difficult. Half had laparoscopic (minimally invasive) surgery and half had open surgery. Researchers measured symptoms and quality of life before and afte…

People with achalasia, a swallowing disorder, have a much higher risk of developing esophageal cancer. This study tested whether spraying a special dye (Lugol) during an endoscopy could help doctors find early signs of cancer (dysplasia) in 39 patients who had achalasia for over …

This study looked at 195 adults with achalasia, a rare condition that makes it hard to swallow. Researchers checked if certain antibodies in the blood are linked to how severe the disease is and how well patients respond to a treatment called POEM. The goal was to see if these an…