Botox for the esophagus: new hope for swallowing pain?

NCT ID NCT01955174

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether injecting botulinum toxin (like Botox) into the lower esophagus can ease symptoms of nutcracker esophagus, a condition that causes chest pain and trouble swallowing. Twenty-four adults received either the toxin or a placebo in a double-blind setup. The main goal was to see if symptoms improved enough to lower their Eckardt score below 3.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Service d'Exploration Fonctionnelle Digestive - Hôpital Edouard Herriot Pavillon H 5 - Hospices Civils de Lyon

    Lyon, 69437, France

  • Service d'Hépato-Gastro-Entérologie et Oncologie Digestive- Hôpital Haut Lévêque - CHU de Bordeaux

    Bordeaux, 33075, France

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