Hyperpigmentation of the skin
MONDO:001928931 clinical trials for this condition and its sub-types, 17 tagged with Hyperpigmentation of the skin itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Hyperpigmentation of the skin
-
Legius syndrome 5 trials
-
Dowling-Degos disease 0 trials · 4 incl. sub-types
4 sub-types
- Dowling-Degos disease 1 4 trials
- Dowling-Degos disease 2 0 trials
- Dowling-Degos disease 4 0 trials
- Dowling-degos disease 3 0 trials
-
Schwannomatosis 3 trials
4 sub-types
- 22q-related schwannomatosis 0 trials
- LZTR1-related schwannomatosis 0 trials
- SMARCB1-related schwannomatosis 0 trials
- Neurofibromatosis, type III, mixed central and peripheral 0 trials
-
3 sub-types
-
H syndrome 0 trials
-
Acromelanosis 0 trials
-
Cafe au lait spots, multiple 0 trials
-
Dermatopathia pigmentosa reticularis 0 trials
-
Familial generalized lentiginosis 0 trials
-
1 sub-type
-
Gastrocutaneous syndrome 0 trials
-
Mosaic Legius syndrome 0 trials
-
Phakomatosis pigmentovascularis 0 trials
3 sub-types
- Phakomatosis cesioflammea 0 trials
- Phakomatosis cesiomarmorata 0 trials
- Phakomatosis spilorosea 0 trials
Most studied deeper sub-types
-
Can a cream stop light from darkening your skin?
Prevention CompletedThis study tested seven different cosmetic creams to see if they could prevent skin darkening caused by high-energy visible light (like from the sun or screens). 33 healthy adults with fair to medium skin had creams applied to their back before being exposed to a specific blue-vi…
Sponsor: Cosmetique Active International • Aim: Prevention
Last updated Jun 27, 2026 12:08 UTC
-
Apple peptides may speed skin healing after cosmetic procedures
Symptom relief CompletedThis trial tests a topical apple peptide complex for improving skin recovery after aesthetic procedures such as liposuction, breast augmentation, laser treatments, and microneedling. Women aged 45 to 65 who have had or are planning such procedures will apply the product to their …
Sponsor: Grow Out Oils Clinical Aromatherapy Company • Aim: Symptom relief
Last updated Sep 10, 2026 00:00 UTC
-
Fizzy drink aimed at erasing dark spots put to the test
Symptom relief CompletedThis study tests whether a daily fizzy drink containing glutathione can safely lighten facial dark spots and improve skin radiance. Sixty adults with hyperpigmentation will take either the active drink or a placebo for several weeks. Researchers will measure changes in pigmentati…
Sponsor: NovoBliss Research Pvt Ltd • Aim: Symptom relief
Last updated Aug 08, 2026 00:03 UTC
-
Green tea compound EGCG put to the test for clearer, more hydrated skin
Symptom relief CompletedThis large-scale trial is testing whether a topical cream containing epigallocatechin gallate (EGCG), a compound from green tea, can reduce facial redness (erythema), dark spots (melanin), and improve skin moisture. Over 300 participants will apply the cream twice daily for 84 da…
Phase 2/3 • Sponsor: Naniek Widyaningrum • Aim: Symptom relief
Last updated Jul 29, 2026 00:00 UTC
-
A skin biostimulator aims to reverse sun damage without the peel downtime
Symptom relief CompletedThis trial tests whether a topical chemical skin biostimulator containing homocysteic acid can improve firmness, wrinkles, texture, and hydration in women aged 39–69 with sun-damaged skin. Twenty-five women receive four treatment sessions two weeks apart, followed by a home-care …
Sponsor: Medical University of Silesia • Aim: Symptom relief
Last updated Jul 25, 2026 00:00 UTC
-
New serums take on hydroquinone in skin brightening showdown
Symptom relief CompletedThis 4-week pilot study tested two brightening serums against 4% hydroquinone in 18 adults with hyperpigmentation or melasma. Each participant used different products on each side of their face to compare results. The goal was to see if the serums could improve skin tone evenness…
Sponsor: Revision Skincare • Aim: Symptom relief
Last updated Jun 27, 2026 13:06 UTC
-
New brightening peel shows promise for sun spots and uneven skin tone
Symptom relief CompletedThis completed study tested a brightening treatment (a type of chemical peel) combined with a retinol serum and post-procedure cream on 11 healthy women aged 20 to 65 with moderate facial pigmentation from sun exposure or blemishes. Participants received four treatment sessions t…
Sponsor: Revision Skincare • Aim: Symptom relief
Last updated Jun 27, 2026 13:03 UTC
-
New serum fights age spots in 16-Week trial
Symptom relief CompletedThis study tested a dark spot corrector serum along with two different skincare routines in 48 women with moderate age spots. Over 16 weeks, doctors checked if the spots got lighter, smaller, or less noticeable. The goal was to see if the treatment was safe and effective for impr…
Sponsor: Revision Skincare • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
-
New laser study aims to erase dark spots safely for darker skin tones
Symptom relief CompletedThis study tested a special laser (1927nm) to reduce dark spots on the face in 15 adults with Fitzpatrick Skin Types V and VI (darker skin). The goal was to see if the laser works and to find the best skin care routine before and after treatment to avoid side effects like scarrin…
Sponsor: University of Texas Southwestern Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
-
Does washing fat before facial grafting give better skin results?
Symptom relief CompletedThis study looked at whether washing fat with saline before injecting it into the face improves skin appearance more than using unwashed fat. Twenty-six healthy women aged 35 to 70 with visible signs of aging received fat grafts on both sides of their face. Researchers measured c…
Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
-
Eyelid Surgery's Long-Term effects on dark circles revealed
Knowledge-focused CompletedThis study looked back at 120 people who had lower eyelid surgery to remove bags. Researchers wanted to see how the surgery affected dark circles and wrinkles around the eyes months to years later. They used photos and rating scales to measure changes in skin color and wrinkle se…
Sponsor: Peking Union Medical College • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC