Hirschsprung disease
MONDO:0018309Hirschsprung disease (HSCR) is a congenital intestinal motility disorder that is characterized by signs of intestinal obstruction due to the presence of an aganglionic segment of variable extent in the terminal part of the colon.
Also known as: HSCR, Hirschsprung disease, Hirschsprung disease susceptibility, Hirschsprung's disease, aganglionic megacolon, congenital intestinal aganglionosis, congenital megacolon, pelvirectal achalasia
26 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
-
Could a simple mineral boost recovery after pediatric colon surgery?
Disease control ENROLLING_BY_INVITATIONThis trial tests whether giving zinc supplements before and after colonic surgery in children can help protect the gut lining and reduce inflammation. Children aged 1 month to 18 years undergoing colonic surgery with anastomosis will be randomly assigned to receive either routine…
Phase: NA • Sponsor: Alexandria University • Aim: Disease control
Last updated Aug 14, 2026 00:00 UTC
-
New canadian registry aims to unlock secrets of rare childhood bowel diseases
Knowledge-focused ENROLLING_BY_INVITATIONThis study creates a long-term registry for children with Hirschsprung's disease or anorectal malformations. It collects health data and family surveys during regular clinic visits to understand outcomes and improve care. No extra tests or procedures are needed. Up to 999 childre…
Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC